Thymosin Alpha-1 Price Comparison

Live prices from 13 SA suppliers, from R605.00, compared side by side so you never overpay.

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Best Price R605.00
Average R814.00
Highest R1,059.00
You Could Save 43%
7 results
Best Price
Save 43%
Helix Collective logo

Thymosin Alpha-1 5mg

In Stock 5mg
R605.00
+ R170.00 delivery
Striata Labs logo

Thymosin Alpha-1 5mg

R650.00
In Stock 5mg Lab Tested
Save 39% + R150.00 delivery
Buy Peptides logo

Thymosin Alpha-1 5mg

R800.00
In Stock 5mg
Save 24% + R250.00 delivery
Peptide Pen logo

Thymosin Alpha-1 5mg

R825.00
In Stock 5mg
Save 22% + R250.00 delivery
Impact Nutrition logo

Thymosin Alpha-1 5mg

R859.00
In Stock 5mg
Save 19% + R250.00 delivery
Atlas Nutrition  logo

Thymosin Alpha-1 5mg

R900.00
In Stock 5mg
Save 15% FREE over R2,000
Impact Nutrition logo

Thymosin Alpha-1 5mg

R1,059.00
In Stock 5mg
+ R250.00 delivery

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Thymosin Alpha-1 Profile

Well Studied

Synthetic Thymic Hormone | Immune System Modulator

Overview

Thymosin Alpha 1 is a synthetic 28-amino acid peptide identical to naturally occurring thymic hormone, studied in 11,000+ patients across 30+ clinical trials with less than 1% serious adverse events. Approved in 35+ countries for immune modulation.

Mechanism of Action

Activates TLR pathways, enhances T-cell maturation, stimulates NK cells, and modulates dendritic cell function via systemic circulation. Injectable route achieves 90-95% bioavailability with 2-hour peak time.

Key Benefits

  • Primary FDA-studied route with extensive clinical validation
  • Maximum immune modulation through systemic circulation
  • Established dosing from 35+ countries of clinical use
  • Exceptional safety profile (<1% serious adverse events)
  • Reduces pro-inflammatory cytokines 40-60%
  • Approved in 35+ countries

Quick Stats

Typical Dose
1.6mg per injection (standard dose across all protocols)
Frequency
2x weekly (e.g., Monday and Thursday) for standard immune support
Cycle Duration
6 months continuous for therapeutic protocols
Storage
Use immediately after reconstitution or refrigerate up to 2 hours

Molecular Information

Molecular Weight
3,108 Da
Length
28 amino acids
Type
Acetylated polypeptide
Half-Life
~2 hours

Amino Acid Sequence

One-letter: ?SDAAVDTSSEITTKDLKEKKEVVEEAEN
Ac
1

Ac

Position 1

Ser
2

Serine

Position 2

Asp
3

Aspartic Acid

Position 3

Ala
4

Alanine

Position 4

Ala
5

Alanine

Position 5

Val
6

Valine

Position 6

Asp
7

Aspartic Acid

Position 7

Thr
8

Threonine

Position 8

Ser
9

Serine

Position 9

Ser
10

Serine

Position 10

Glu
11

Glutamic Acid

Position 11

Ile
12

Isoleucine

Position 12

Thr
13

Threonine

Position 13

Thr
14

Threonine

Position 14

Lys
15

Lysine

Position 15

Asp
16

Aspartic Acid

Position 16

Leu
17

Leucine

Position 17

Lys
18

Lysine

Position 18

Glu
19

Glutamic Acid

Position 19

Lys
20

Lysine

Position 20

Lys
21

Lysine

Position 21

Glu
22

Glutamic Acid

Position 22

Val
23

Valine

Position 23

Val
24

Valine

Position 24

Glu
25

Glutamic Acid

Position 25

Glu
26

Glutamic Acid

Position 26

Ala
27

Alanine

Position 27

Glu
28

Glutamic Acid

Position 28

Asn
29

Asparagine

Position 29

N-terminus C-terminus
Hydrophobic
Polar
Positive (+)
Negative (-)
Modified

Modifications

N-terminal acetylated Synthetically identical to naturally occurring thymic hormone

Research Indications

The following information is derived from published scientific literature and is provided for educational and research reference purposes only. It does not constitute medical advice, diagnosis, or treatment recommendations. These peptides are not approved for human use and are sold exclusively for in-vitro laboratory research.

Primary Immunodeficiencies

Most Effective

FDA orphan designation for DiGeorge syndrome; restores T-cell function.

Vaccine Enhancement

Most Effective

Improved antibody responses in elderly and hemodialysis patients (H1N1, COVID-19).

HIV/AIDS Support

Effective

Restores CD4+ counts and reduces opportunistic infections.

Cytokine Reduction

Effective

Reduces pro-inflammatory cytokines TNF-α, IL-1β, IL-6 by 40-60%.

Hepatitis B/C Support

Effective

Enhanced antiviral efficacy when combined with interferon.

Autoimmune Conditions

Moderate

Helps manage inflammatory autoimmune conditions.

Post-Surgical Immune Restoration

Moderate

Restores immune function after surgical stress.

Exercise-Induced Immunosuppression

Moderate

Manages immune suppression from intense training.

Thymic Regeneration Support

Moderate

Supports thymus gland function with aging.

Immune Senescence Delay

Moderate

Delays age-related immune decline in elderly populations.

Dosing Protocols

injectable

Subcutaneous injection is the primary route with 90-95% bioavailability. Standard dosing is 1.6mg twice weekly.

Goal Dose Frequency Route
Standard immune support 1.6mg 2x weekly SubQ
Acute conditions (sepsis) 1.6mg 2x daily for 5 days, then daily SubQ/IM
Cancer/hepatitis support 1.6mg 2x weekly SubQ
Maintenance/prevention 1.6mg 2x weekly SubQ

Key Tips

  • Abdomen, thigh injection sites
  • Rotate to prevent irritation
  • 90-95% bioavailability
Materials Needed
Thymosin Alpha 1 lyophilized powder Sterile water (1.0mL) Insulin syringes Alcohol swabs
Steps
  1. 1 Clean work surface thoroughly
  2. 2 Add 1.0mL sterile water slowly to lyophilized powder
  3. 3 Inject water down vial side (avoid direct powder contact)
  4. 4 Gently swirl until fully dissolved (never shake)
  5. 5 Final concentration: 1.6mg/mL
  6. 6 Use immediately or refrigerate up to 2 hours

nasal

Intranasal spray with limited data. Requires compounding pharmacy preparation with 40-60% bioavailability vs injectable.

Goal Dose Frequency Route
General support 500mcg per nostril 2x daily Nasal spray
Enhanced support 1000mcg per nostril 2x daily Nasal spray
Maintenance 500mcg per nostril 1x daily Nasal spray

Key Tips

  • Non-invasive
  • 40-60% bioavailability vs injectable
  • Requires compounding pharmacy

Peptide Interactions

Immunosuppressive Agents

Avoid

Fatal graft rejection risk in transplant patients - contraindicated.

Corticosteroids

Monitor

Pharmacodynamic antagonism possible.

Interferon-α

Synergistic

Enhanced antiviral efficacy in hepatitis treatment.

Vaccines

Compatible

Enhances vaccine immunogenicity.

Chemotherapy

Compatible

Protective against bone marrow damage.

What to Expect

Week 1-2

Initial immune system activation

Week 2-6

Enhanced immune function, reduced infection risk

Week 6-12

Maximum immunomodulatory benefits

Week 12+

Sustained immune support with continued use

Side Effects & Safety

Common Side Effects

  • Mild injection site reactions (<10% incidence)
  • Generally well-tolerated with exceptional safety record

Monitoring

  • Monitor for hypersensitivity with first dose
  • Watch for first-dose immune activation symptoms

Stop Signs

  • Signs of graft rejection in transplant recipients
  • Persistent injection site reactions or infection signs
  • Unusual immune system hyperactivity
  • Severe allergic reactions (rare)

Contraindications

  • Organ transplant recipients (risk of graft rejection)
  • Pregnancy and breastfeeding

Quality Checklist

Good Signs

  • White, fluffy lyophilized powder filling vial bottom
  • Crystal clear solution after reconstitution (no particles/cloudiness)
  • Professional pharmaceutical labeling with batch numbers, expiration

Warning Signs

  • Minor powder compaction during shipping (acceptable if dissolves cleanly)

Bad Signs

  • Yellow, brown, or collapsed powder (heat/moisture degradation)
  • Persistent cloudiness or particles post-reconstitution
  • Non-professional sourcing or unclear labeling

Research & References

Key References

  1. 2020

    COVID-19 Treatment Study

    30% vs 11% mortality reduction in severe cases; lymphocyte restoration.

  2. 2020

    TESTS Phase 3 Sepsis Trial

    1,106 patients; mixed overall results but subgroup benefits in elderly/diabetic populations.

  3. 2020

    Cytokine Storm Mitigation Study

    40-60% reduction in pro-inflammatory cytokines (TNF-α, IL-1β, IL-6).

  4. 2024

    Comprehensive Safety Review

    11,000+ patients, 30+ trials; <1% serious adverse events.

Search PubMed for Thymosin Alpha-1

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