TB-500 Price Comparison

Live prices from 32 SA suppliers, from R310.00, compared side by side so you never overpay.

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Best Price R330.00
Average R330.00
Highest R330.00
3 results
Best Price
Blaque Sigma logo

TB-500 2mg

In Stock 2mg Lab Tested
R330.00
+ R150.00 delivery
SA Peptides logo

TB-500 2mg

R330.00
In Stock 2mg
+ R140.00 delivery
Buy Peptides logo

TB-500 2mg

R330.00
In Stock 2mg
+ R250.00 delivery

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TB-500 Profile

Well Studied

Synthetic Fragment (17-23) of Thymosin Beta-4

Overview

A synthetic 7-amino acid fragment corresponding to the actin-binding region of thymosin beta-4, originally developed for equine use with retained tissue repair properties. TB-500 acts as principal actin-sequestering protein, regulating cell migration, promoting angiogenesis, reducing inflammation, and activating stem cell differentiation.

Mechanism of Action

Acts as principal actin-sequestering protein, regulating cell migration, promoting angiogenesis, reducing inflammation, and activating stem cell differentiation for comprehensive regenerative effects.

Key Benefits

  • Superior systemic tissue repair
  • Accelerated muscle, tendon, and ligament healing
  • Enhanced cell migration and angiogenesis
  • Comprehensive regenerative effects
  • Neuroprotective properties

Quick Stats

Typical Dose
2-5mg per injection (higher doses for serious injuries)
Frequency
2-3x weekly (e.g., Monday, Wednesday, Friday)
Cycle Duration
6-8 weeks for active healing
Storage
Reconstituted: 2-8°C, use within 28 days

Molecular Information

Molecular Weight
4,963.44 Da
Length
43 amino acids
Type
Thymosin fragment
Half-Life
~2 hours

Amino Acid Sequence

One-letter: ?SDKPDMAEIEKFDKSKLKKTETQEKNPLPSKETIEQEKQAGES
Ac
1

Ac

Position 1

Ser
2

Serine

Position 2

Asp
3

Aspartic Acid

Position 3

Lys
4

Lysine

Position 4

Pro
5

Proline

Position 5

Asp
6

Aspartic Acid

Position 6

Met
7

Methionine

Position 7

Ala
8

Alanine

Position 8

Glu
9

Glutamic Acid

Position 9

Ile
10

Isoleucine

Position 10

Glu
11

Glutamic Acid

Position 11

Lys
12

Lysine

Position 12

Phe
13

Phenylalanine

Position 13

Asp
14

Aspartic Acid

Position 14

Lys
15

Lysine

Position 15

Ser
16

Serine

Position 16

Lys
17

Lysine

Position 17

Leu
18

Leucine

Position 18

Lys
19

Lysine

Position 19

Lys
20

Lysine

Position 20

Thr
21

Threonine

Position 21

Glu
22

Glutamic Acid

Position 22

Thr
23

Threonine

Position 23

Gln
24

Glutamine

Position 24

Glu
25

Glutamic Acid

Position 25

Lys
26

Lysine

Position 26

Asn
27

Asparagine

Position 27

Pro
28

Proline

Position 28

Leu
29

Leucine

Position 29

Pro
30

Proline

Position 30

Ser
31

Serine

Position 31

Lys
32

Lysine

Position 32

Glu
33

Glutamic Acid

Position 33

Thr
34

Threonine

Position 34

Ile
35

Isoleucine

Position 35

Glu
36

Glutamic Acid

Position 36

Gln
37

Glutamine

Position 37

Glu
38

Glutamic Acid

Position 38

Lys
39

Lysine

Position 39

Gln
40

Glutamine

Position 40

Ala
41

Alanine

Position 41

Gly
42

Glycine

Position 42

Glu
43

Glutamic Acid

Position 43

Ser
44

Serine

Position 44

N-terminus C-terminus
Hydrophobic
Polar
Positive (+)
Negative (-)
Modified

Modifications

N-terminal acetylation for enhanced stability

Research Indications

The following information is derived from published scientific literature and is provided for educational and research reference purposes only. It does not constitute medical advice, diagnosis, or treatment recommendations. These peptides are not approved for human use and are sold exclusively for in-vitro laboratory research.

Muscle Regeneration

Most Effective

Accelerated healing of muscle fibers with reduced recovery time and enhanced repair via cell migration and differentiation.

Tendon & Ligament Healing

Most Effective

Connective tissue repair with reduced scar formation and improved biomechanical properties of healing tissues.

Wound Healing

Most Effective

Enhanced dermal closure, improved angiogenesis, and reduced inflammation in acute and chronic scenarios.

Exercise Recovery

Effective

Faster recovery from intense training with reduced muscle soreness and improved tissue repair.

Injury Prevention

Effective

Strengthened tissues through enhanced repair mechanisms may reduce injury risk.

Performance Enhancement

Moderate

Improved muscle quality through enhanced regeneration and repair pathways.

Neuroprotection

Moderate

Protective effects against neuronal damage in various models.

Spinal Cord Injury Support

Moderate

Preclinical evidence for improved outcomes in spinal injury models.

Brain Health

Emerging

Potential neuroprotective and regenerative effects on brain tissue.

Dosing Protocols

injectable

Subcutaneous or intramuscular injection. Flexible timing with no empty stomach requirement. Can be injected near injury site for localized effect.

Goal Dose Frequency Route
General tissue repair 2-3mg 2x weekly SubQ or IM
Serious injury recovery 4-5mg 3x weekly SubQ near injury site
Athletic enhancement 2-3mg 2x weekly SubQ
Chronic conditions 3-4mg 2-3x weekly SubQ or IM
Maintenance 2mg 1-2x weekly SubQ
Post-surgical recovery 3-5mg 3x weekly SubQ

Key Tips

  • Subcutaneous injection at belly, thigh, or shoulder
  • Intramuscular option for larger muscles
  • Flexible timing - no empty stomach required
Materials Needed
Bacteriostatic water (BAC) Insulin syringes (1mL recommended) Alcohol swabs TB-500 vial (2mg or 5mg typical) Sterile work surface
Steps
  1. 1 Clean work area and hands thoroughly with alcohol
  2. 2 Calculate required BAC water volume
  3. 3 Draw calculated BAC water slowly into syringe
  4. 4 Inject BAC water slowly down vial side (never directly on powder)
  5. 5 Gently swirl vial until powder completely dissolves
  6. 6 Store reconstituted solution refrigerated, use within 28 days

topical

Topical formulations available for specific applications including wound healing and eye conditions.

Goal Dose Frequency Route
Chronic wound healing 0.01-0.03% concentration 1-2x daily Topical application
Dry eye treatment Eye drops formulation As directed Ophthalmic

Key Tips

  • Direct application to affected area
  • Non-invasive option
  • Suitable for surface wounds and eye conditions

Peptide Interactions

BPC-157

Synergistic

Complementary healing mechanisms with enhanced tissue repair when combined (Wolverine Stack).

Ipamorelin

Compatible

May enhance tissue sensitivity to growth hormone effects.

CJC-1295

Synergistic

Combined tissue repair with GH-releasing effects for comprehensive recovery.

IGF-1

Synergistic

Enhanced muscle and tissue regeneration through complementary growth pathways.

GHRP-6

Compatible

No negative interactions; potential enhanced recovery.

Melanotan II

Compatible

Different receptor families with no pathway overlap.

What to Expect

Week 1-2

Reduced inflammation and improved tissue sensation

Week 2-4

Accelerated healing rate and improved tissue quality

Week 4-8

Maximum tissue repair and regenerative benefits

Week 6-12

Continued improvement in tissue strength and function

Side Effects & Safety

Common Side Effects

  • Generally minimal side effects
  • Possible mild injection site reactions
  • Temporary fatigue in some users

Stop Signs

  • Persistent or worsening injection site infections
  • Unusual swelling or prolonged redness
  • Severe allergic reactions
  • Unexpected systemic symptoms
  • Concerning health changes

Contraindications

  • Active cancer treatment (due to angiogenic effects)
  • Pregnancy or breastfeeding
  • Immunosuppressive medications (consult provider)
  • WADA prohibited for competitive athletes

Quality Checklist

Good Signs

  • White lyophilized powder - fine, evenly distributed with light fluffy texture
  • Clear, colorless solution after reconstitution with no particles
  • Proper vacuum seal intact with secure rubber stopper

Warning Signs

  • Slight powder clumping acceptable if completely dissolves with gentle swirling

Bad Signs

  • Colored or crystalline powder (yellow/brown indicates degradation)
  • Persistent cloudiness, floating particles, or precipitation
  • Damaged vial seal or contamination signs

Research & References

Latest Research

March 2024

TB-500 Metabolism and Detection in Clinical Applications

Journal of Chromatography B

Analysis of TB-500 metabolic pathways and bioavailability in human subjects for clinical dosing protocols.

June 2021

Thymosin Beta-4 in Anti-Aging Regenerative Therapies

Cells Journal

Review of TB-500's ability to reactivate embryonic developmental processes in adult organs for regenerative medicine.

Key References

  1. 2012

    Dermal Wound Healing Study

    Significant acceleration in wound healing rates in patients with chronic pressure ulcers and venous stasis ulcers compared to placebo in Phase 2 human trial.

  2. 2016

    Cardiac Tissue Regeneration

    TB-500 pre-treated endothelial cells improved left ventricular function by greater than 50% in post-MI subjects in human clinical trial.

  3. 2015

    Muscle Fiber Regeneration

    Improved skeletal muscle fiber regeneration in dystrophin-deficient mice, showing potential for muscular dystrophy treatment.

  4. 2014

    Corneal Healing Research

    Topical TB-500 significantly improved signs and symptoms of moderate to severe dry eye with lasting effects in Phase 2 human trial.

Search PubMed for TB-500

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