Live prices from 8 SA suppliers, from R280.00, compared side by side so you never overpay.
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Compare 2 prices for Sermorelin. Cheapest: R750.00. Average: R775.00.
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White Rabbit Labs
Best
Sermorelin 10mg |
R750.00 | R75.00/mg | In Stock | R120.00 |
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Sermorelin 10mg |
R800.00 | R80.00/mg | In Stock | Free over R4,000 |
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GHRH Analog | Growth Hormone Releasing Hormone
Sermorelin is a synthetic 29-amino acid analog of human growth hormone-releasing hormone that stimulates natural growth hormone production while preserving physiological pulsatile patterns. Originally FDA-approved in 1997 for pediatric GH deficiency, it was discontinued in 2008 for manufacturing reasons, not safety concerns.
Subcutaneous injection provides optimal bioavailability for binding GHRH receptors, stimulating pulsatile GH release while maintaining hypothalamic-pituitary axis integrity and allowing natural somatostatin negative feedback.
1.26kg lean mass increase documented in elderly men with improved muscle strength tests.
Endogenous IGF-1 stimulation drives protein synthesis and muscle growth.
Enhanced recovery through physiological GH stimulation.
Doubles 12-hour GH release in elderly subjects over 6 weeks.
Decreased adiposity and improved lean mass distribution.
Improved skin thickness and quality.
Preserves natural axis function without suppression.
Maintains physiological GH release patterns.
Subcutaneous injection is the primary method. Bedtime administration aligns with natural nocturnal GH pulses. Avoid food 2+ hours before injection as carbohydrates blunt GH response.
| Goal | Dose | Frequency | Route |
|---|---|---|---|
| Anti-aging/Longevity | 200-300mcg | Once at bedtime | SubQ |
| Athletic Performance | 300-500mcg | Once at bedtime | SubQ |
| Body Composition | 200mcg | 5 days weekly | SubQ |
| Combination Therapy | 200mcg + GHRP | Once daily | SubQ co-injection |
Intranasal spray is available with 69% patient preference over injection. Lower bioavailability but bypasses first-pass metabolism.
| Goal | Dose | Frequency | Route |
|---|---|---|---|
| Nasal administration | 30+ mcg/kg | Once daily at bedtime | Nasal spray |
Excellent combination producing 3-5 fold increases in GH release.
Highly effective combination - CJC-1295 provides sustained 6-8 day release while sermorelin offers immediate pulsatile effects.
Combined GHRH+GHRP-2 produces 54-fold GH increases compared to 20-fold with GHRH alone.
Somatostatin analogs directly block GH release by activating inhibitory receptors.
High-dose glucocorticoids suppress pituitary GH release and reduce GHRH receptor sensitivity.
GH antagonizes insulin action; monitor combination closely.
Essential combination as untreated hypothyroidism prevents sermorelin response.
IGF-1 elevation begins; improved sleep quality and recovery
Body composition changes begin; increased energy and well-being
Visible muscle tone improvements; fat reduction; skin quality enhancement
Sustained improvements; optimal IGF-1 elevation
Maximum benefits: muscle growth, fat loss, anti-aging effects
Pivotal trial with 110 prepubertal GH-deficient children demonstrating sustained efficacy through 36 months. Height velocity increased from 4.1 to 8.0 cm/year.
Landmark study demonstrating reversal of age-related GH/IGF-1 decline in 60-78 year old males. Doubled 12-hour GH release over 6 weeks.
Comprehensive analysis showing 11-12 minute half-life and 6% bioavailability for subcutaneous administration.
1.26kg lean mass increase with improved muscle strength; decreased systolic BP.
69% patient preference over injection with reliable therapeutic response at 30+ mcg/kg.
Plain-English guides and study summaries from published literature.
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