Selank Price Comparison

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Best Price R700.00
Average R700.00
Highest R700.00
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Limitless Peptides logo

Selank 11mg

In Stock 11mg Lab Tested
R700.00
+ R90.00 delivery

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Selank Profile

Well Studied

Anxiolytic & Nootropic Peptide | Tuftsin Analog

Overview

Selank is a synthetic heptapeptide analog of the naturally occurring immune peptide tuftsin, developed by the Russian Academy of Sciences. It provides anxiolytic effects comparable to benzodiazepines but without sedation, amnesia, tolerance, or withdrawal.

Mechanism of Action

Works through allosteric modulation of GABA-A receptors, serotonin and dopamine system optimization, enkephalin degradation inhibition, IL-6 and cytokine balance regulation, and BDNF upregulation in the hippocampus.

Key Benefits

  • Rapid onset anxiolytic effects
  • Enhanced BDNF expression (30% increase)
  • Improved stress resilience
  • Cognitive enhancement
  • Immune modulation
  • No tolerance or withdrawal
  • Neuroprotective effects

Quick Stats

Typical Dose
250-500mcg per dose
Frequency
1-2x daily (morning and/or evening)
Cycle Duration
2-8 weeks on
Storage
Reconstituted: 2-8°C, use within 30 days

Molecular Information

Molecular Weight
751.89 Da
Length
7 amino acids
Type
Tuftsin analog
Half-Life
2-10 minutes

Amino Acid Sequence

One-letter: TKPRPGP
Thr
1

Threonine

Position 1

Lys
2

Lysine

Position 2

Pro
3

Proline

Position 3

Arg
4

Arginine

Position 4

Pro
5

Proline

Position 5

Gly
6

Glycine

Position 6

Pro
7

Proline

Position 7

N-terminus C-terminus
Hydrophobic
Polar
Positive (+)
Negative (-)
Modified

Modifications

Synthetic analog of tuftsin with anxiolytic properties

Research Indications

The following information is derived from published scientific literature and is provided for educational and research reference purposes only. It does not constitute medical advice, diagnosis, or treatment recommendations. These peptides are not approved for human use and are sold exclusively for in-vitro laboratory research.

Generalized Anxiety Disorder

Most Effective

Clinical trials show significant reduction in anxiety symptoms comparable to benzodiazepines but without sedation or amnesia.

Post-Traumatic Stress Disorder

Effective

Research indicates effectiveness in PTSD treatment.

Social Anxiety

Effective

Reduces anticipatory anxiety and performance stress.

Memory Enhancement

Effective

Improves memory consolidation and learning capacity.

Attention and Focus

Effective

Enhanced sustained attention during demanding cognitive tasks.

Neuroprotection

Effective

BDNF upregulation supports long-term brain health.

Immune Modulation

Moderate

Balances immune system function through cytokine regulation.

Antiviral Activity

Moderate

Shows activity against influenza, HSV, and cytomegalovirus.

Inflammation Regulation

Moderate

Modulates inflammatory gene expression.

Dosing Protocols

injectable

Subcutaneous injection is the primary method with well-documented protocols. Provides reliable absorption and dosing.

Goal Dose Frequency Route
Mild anxiety relief 250mcg 1x daily SubQ
Moderate anxiety/cognitive 250mcg 2x daily (morning & evening) SubQ
Intensive anxiety support 500mcg 1x daily (divided doses) SubQ
Cognitive enhancement 250-350mcg 1x daily (morning) SubQ
PTSD support 250mcg 2x daily SubQ
Immune support 250mcg 1x daily for 2-4 weeks SubQ

Key Tips

  • Reliable absorption
  • Precise dosing
  • Well-documented protocols
Materials Needed
Selank lyophilized powder vial Bacteriostatic water Insulin syringes (29-31 gauge) Alcohol wipes Sterile work surface
Steps
  1. 1 Remove vial from refrigeration; allow 10-15 minutes to reach room temperature
  2. 2 Clean vial tops with alcohol wipes using circular motion; air dry
  3. 3 Calculate reconstitution volume for desired concentration
  4. 4 Draw bacteriostatic water into insulin syringe; remove air bubbles
  5. 5 Insert needle at 45-degree angle against glass wall
  6. 6 Slowly inject BAC water down vial side to minimize foaming
  7. 7 Remove needle and gently swirl vial (never shake vigorously)
  8. 8 Allow 1-2 minutes if cloudiness remains; swirl until clear
  9. 9 Verify final solution is clear and colorless
  10. 10 Label with reconstitution date and concentration
  11. 11 Refrigerate immediately; use within 30 days

nasal

Intranasal spray provides fastest onset (15-30 minutes) and is non-invasive. Popular for as-needed anxiety relief.

Goal Dose Frequency Route
Acute anxiety relief 300-600mcg (1-2 sprays) Once daily or as-needed Nasal spray

Key Tips

  • Fastest onset (15-30 minutes)
  • Duration 4-6 hours
  • No injection required
  • Convenient for as-needed use

Peptide Interactions

Semax

Synergistic

Enhanced cognitive and anxiolytic effects when combined.

BPC-157

Compatible

Complementary stress response mechanisms.

Noopept

Compatible

Both enhance BDNF via different pathways.

Phenylpiracetam

Compatible

Balanced anxiety relief and cognition enhancement.

Benzodiazepines

Monitor

Similar GABAergic effects; medical supervision advised.

SSRI Antidepressants

Monitor

Can combine for enhanced mood regulation; monitor closely.

Modafinil

Compatible

Balanced anxiety reduction and wakefulness.

Alcohol

Avoid

Both affect GABA system; risk of excessive sedation.

What to Expect

30-60 minutes

Mild anxiety reduction begins

1-3 days

Improved mental clarity and focus

1 week

Enhanced stress resilience and emotional stability

1-2 weeks

Peak cognitive enhancement effects

Post-discontinuation

Sustained benefits for several days

Side Effects & Safety

Common Side Effects

  • Minimal side effects - excellent safety profile
  • No sedation or cognitive impairment
  • No tolerance, dependence, or withdrawal

Monitoring

  • Start with lowest effective dose (250mcg)
  • Refrigerate properly to maintain stability
  • Use sterile injection techniques
  • Monitor mood and anxiety levels

Stop Signs

  • Severe allergic reactions (rash, breathing difficulty, swelling)
  • Persistent injection site reactions or infection signs
  • Unusual mood changes or increased anxiety
  • Severe headaches or neurological symptoms
  • Contaminated product signs (unusual smell, cloudiness)
  • Unexplained fatigue or cognitive impairment
  • Skin reactions or immune hypersensitivity

Contraindications

  • Known peptide allergies
  • Pregnancy or breastfeeding
  • Consult healthcare provider with multiple psychiatric medications

Quality Checklist

Good Signs

  • White to off-white lyophilized powder without clumping
  • Clear, colorless reconstituted solution
  • Clear batch information, purity testing, expiration dates
  • Appropriate packaging and cold shipping

Warning Signs

  • Unusual smell or burning sensation may indicate bacterial contamination
  • Room temperature shipping of nasal spray

Bad Signs

  • Yellowing, clumping, or moisture exposure
  • Persistent cloudiness after reconstitution

Research & References

Latest Research

March 2024

Inflammation-Related Gene Expression Modulation

Neuroscience Research

New findings on Selank's effects on inflammatory gene expression.

January 2024

Comparison with Classical Benzodiazepines

Psychopharmacology Journal

Comparative study showing similar efficacy without benzodiazepine side effects.

November 2023

Antiviral Activity Study

Antiviral Research

Demonstrated activity against influenza, HSV, and cytomegalovirus.

Key References

  1. 2016

    GABAergic Gene Expression Study

    Rat frontal cortex study at 300mcg/kg showed modulation of 45 genes involved in neurotransmission; GABAergic mechanism confirmed.

  2. 2008

    GAD Clinical Trial

    Human subjects showed significant anxiolytic and mild nootropic effects lasting up to one week post-administration.

  3. 2010

    BDNF Enhancement Study

    Rat hippocampus study at 250-500mcg/kg showed 30% increase in hippocampal BDNF levels.

  4. 2007

    Memory Consolidation Study

    Significant activation of learning processes in subjects with poor initial learning.

Search PubMed for Selank

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