Pinealon Price Comparison

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Best Price R710.00
Average R808.75
Highest R900.00
You Could Save 21%
4 results
Best Price
Save 21%
White Rabbit Labs logo

Pinealon 20mg

In Stock 20mg
R710.00
+ R120.00 delivery
Peptide Warehouse logo

Pinealon 20mg

R725.00
In Stock 20mg Lab Tested
Save 19% + R95.00 delivery
SA Peptides logo

Pinealon 20mg

R900.00
In Stock 20mg
+ R140.00 delivery
Buy Peptides logo

Pinealon 20mg

R900.00
In Stock 20mg
+ R250.00 delivery

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Pinealon Profile

Well Studied

Synthetic Tripeptide | Neuroprotection & Cognitive Enhancement

Overview

Developed in Russia, Pinealon demonstrates unique DNA-interaction for neuroprotection and cognitive enhancement. Benefits traumatic brain injury recovery and age-related cognitive decline with excellent safety profile.

Mechanism of Action

Penetrates nuclear membranes to directly interact with DNA, modulates gene expression via histone H1.3 binding and MAPK/ERK pathway activation.

Key Benefits

  • Direct DNA interaction
  • Neuroprotection
  • Cognitive enhancement
  • Excellent safety profile
  • 40+ years of clinical use in Russia

Quick Stats

Typical Dose
Injectable: 5mg daily or 100-300mcg daily; Oral: 0.2mg twice daily
Frequency
Injectable: daily for 20 days; Oral: morning and afternoon on empty stomach
Cycle Duration
20 days per cycle
Storage
Refrigerate at 2-8°C, use within 30 days after reconstitution

Molecular Information

Molecular Weight
418.4 Da
Length
3 amino acids
Type
Tripeptide
Half-Life
Not established

Amino Acid Sequence

One-letter: ED?
Glu
1

Glutamic Acid

Position 1

Asp
2

Aspartic Acid

Position 2

Arg
3

Arg (EDR)

Position 3

N-terminus C-terminus
Hydrophobic
Polar
Positive (+)
Negative (-)
Modified

Modifications

Synthetic bioregulator with direct DNA interaction capabilities

Research Indications

The following information is derived from published scientific literature and is provided for educational and research reference purposes only. It does not constitute medical advice, diagnosis, or treatment recommendations. These peptides are not approved for human use and are sold exclusively for in-vitro laboratory research.

Traumatic Brain Injury

Most Effective

Clinical protocol of 5mg daily showed significant cognitive improvements in 72-patient study.

Direct CNS Delivery

Effective

Subcutaneous administration allows systemic circulation to brain tissue for neuroprotective effects.

Cellular Protection

Effective

Caspase-3 suppression, ROS reduction, and excitotoxicity protection.

Memory Enhancement

Effective

Enhanced neurotransmitter function with 1.9x serotonin increase in cell cultures.

NMDA Receptor Expression

Effective

100 ng/kg optimal dose improved spatial learning in hippocampus.

Cellular Senescence Reduction

Moderate

Irisin expression increases linked to telomere protection and mitochondrial enhancement.

Biological Age Markers

Moderate

32-patient study showed significant improvements in aging indicators over 20-30 days.

Dosing Protocols

injectable

Highest bioavailability, direct systemic delivery, established clinical protocols.

Goal Dose Frequency Route
Neuroprotection 5mg daily Once daily SubQ
Cognitive Enhancement 100-300mcg Daily or every other day SubQ
Anti-aging 5mg 20 days, 2-3x yearly SubQ

Key Tips

  • Highest bioavailability
  • Direct systemic delivery
  • Established clinical protocols
Materials Needed
Lyophilized Pinealon powder Bacteriostatic water for injection Insulin syringes (30-31 gauge) Alcohol swabs
Steps
  1. 1 Remove powder and water from refrigeration
  2. 2 Clean vial tops with alcohol swabs; allow to dry
  3. 3 Draw bacteriostatic water into syringe
  4. 4 Inject water slowly down vial side to avoid foam
  5. 5 Gently swirl until completely dissolved
  6. 6 Store at 2-8°C
  7. 7 Use within 30 days

oral

Convenient, proven clinical efficacy. Ultra-short peptide structure survives gastric acid.

Goal Dose Frequency Route
Cognitive Enhancement 0.2mg twice daily Morning and afternoon Empty stomach
Sleep Support 200mcg Daily Oral

Key Tips

  • Convenient administration
  • 3-amino acid structure achieves systemic absorption
  • Proven clinical efficacy

nasal

Theoretical nose-to-brain delivery, potential rapid CNS access. Limited data available.

Key Tips

  • Potential direct brain access
  • Non-invasive
  • Requires further research

Peptide Interactions

Epitalon

Synergistic

Enhanced neuroprotection through complementary telomerase activation pathways.

Cortexin

Synergistic

Synergistic cognitive recovery in stroke patients through brain region targeting.

Thymalin

Compatible

Safe combination supporting neural-immune axis optimization.

Melatonin

Monitor

Monitor sleep patterns; Pinealon stimulates endogenous serotonin production.

BPC-157

Compatible

Different mechanisms with no known interactions.

NAD+

Compatible

Complementary anti-aging mechanisms.

What to Expect

Week 1-2

Improved mental clarity and focus

Week 2-3

Enhanced cognitive processing and memory

Week 3-4

Peak neuroprotective and anti-aging benefits

Side Effects & Safety

Common Side Effects

  • Minimal injection site reactions
  • Mild gastrointestinal adjustment
  • Occasional headache
  • Fatigue

Monitoring

  • Medical supervision recommended
  • Rotate injection sites
  • Use sterile technique

Stop Signs

  • Severe headaches or mood changes
  • Persistent injection site reactions
  • Signs of infection at injection site
  • Unusual neurological symptoms
  • Allergic reactions

Contraindications

  • Pregnancy
  • Lactation

Quality Checklist

Good Signs

  • White crystalline powder; proper freeze-drying indicated
  • Clear reconstituted solution; no particles or cloudiness
  • Pharmaceutical packaging with batch numbers from reputable sources

Warning Signs

  • Ensure distinction between research (lab only) and pharmaceutical (human use) grade

Bad Signs

  • Discolored powder (yellow or brown) indicates degradation from heat or moisture
  • Cloudy solution indicates contamination

Research & References

Key References

  1. 2015

    Human Clinical Trial - Post-Traumatic Cerebrasthenia

    72 patients aged 30-74; 0.2mg twice daily; 20-30 days. Improved memory, reduced headache severity, and enhanced emotional stability compared to controls.

  2. 2015

    Aging Study - Polymorbidity Patients

    32 patients aged 41-83; variable dosing; 30 days. Significant improvements in biological aging biomarkers with anabolic effects.

  3. 2020

    Diabetic Rat Model - Spatial Learning

    100 ng/kg optimal dose; 14 days. Enhanced NMDA receptor expression in hippocampus with neuroplasticity improvements.

  4. 2021

    5xFAD Alzheimer's Mouse Model

    400 μg/kg IP daily; 28 days. Prevention of dendritic spine loss through MAPK/ERK pathway modulation.

Search PubMed for Pinealon

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