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Compare 2 prices for Hexarelin. Cheapest: R250.00. Average: R765.00.
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Crono Pharm
Best
Hexarelin |
R250.00 | R50.00/mg | In Stock | R150.00 |
Lab Tested
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Hexarelin 5mg |
R1,280.00 | R256.00/mg | In Stock | R250.00 |
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Examorelin | Synthetic Growth Hormone Secretagogue
Hexarelin is one of the most potent synthetic growth hormone secretagogues available. It stimulates GH release by binding to the GHS-R1a receptor in the pituitary and hypothalamus, mimicking the action of ghrelin. Notably, Hexarelin demonstrates synergistic effects when combined with GHRH, producing GH responses greater than the arithmetic sum of either peptide alone. It also shows unique cardioprotective properties mediated through the CD36 receptor.
Hexarelin binds to the growth hormone secretagogue receptor 1a (GHS-R1a) in the brain and pituitary gland. This binding initiates a signaling cascade that stimulates somatotroph cells in the anterior pituitary to produce and release growth hormone. Hexarelin also has slight, dose-dependent effects on prolactin, ACTH, and cortisol release. Its cardioprotective effects are mediated through CD36 receptor activation and modulation of calcium channels in cardiomyocytes.
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Histidine
Position 1
D
Position 2
2
Position 3
methyl
Position 4
Tryptophan
Position 5
Alanine
Position 6
Tryptophan
Position 7
D
Position 8
Phenylalanine
Position 9
Lysine
Position 10
NH2
Position 11
Most potent GHRP for stimulating endogenous growth hormone release from the pituitary.
Produces synergistic GH release when combined with GHRH, greater than sum of individual effects.
Significant increases in IGF-1 levels through enhanced GH secretion.
Protective effects on cardiac tissue mediated through CD36 receptor activation.
Reduces apoptosis of cardiomyocytes and controls cardiac action potential.
Cardiotropic effects mediated by elevation of Ca2+ influx through voltage-gated calcium channels.
Beneficial effects on lipid metabolism via CD36 receptor in non-obese insulin-resistant models.
Improved lean mass to fat ratio through GH and IGF-1 elevation.
Subcutaneous or intramuscular injection. Hexarelin is rapidly absorbed after subcutaneous administration and demonstrates stability against proteolytic enzymes. Best administered on empty stomach.
| Goal | Dose | Frequency | Route |
|---|---|---|---|
| GH optimization | 100 mcg | 2-3x daily | SubQ or IM |
| Enhanced results | 200 mcg | 2-3x daily | SubQ or IM |
| With GHRH (synergy) | 100 mcg each | 2-3x daily | SubQ (combined) |
| Cardioprotection | 100-200 mcg | 1-2x daily | SubQ |
Powerful synergy; combination produces GH response greater than sum of individual effects.
Research confirms synergistic GH release when co-administered.
Similar mechanism; typically not stacked together but can be alternated.
Same receptor target; Hexarelin is more potent with less appetite stimulation.
Both are GHRPs; Hexarelin is more potent but may have more side effects.
GH spike within 15-30 minutes of injection
Improved sleep quality and recovery
Enhanced energy and well-being
Noticeable improvements in body composition
Maximum benefits; consider cycling to prevent desensitization
Endocrinology
Hexarelin treatment improved lipid metabolism via CD36 receptor in non-obese insulin-resistant MKR mice.
European Journal of Endocrinology
Demonstrated synergistic GH response when hexarelin co-administered with GHRH, greater than arithmetic sum.
Neuroendocrinology
Hexarelin significantly increased pituitary and hypothalamic GHS-R1a mRNA levels.
Drug Metabolism and Disposition
Half-life of 75.9 min; rapidly absorbed subcutaneously; stable against proteolytic enzymes.
Plain-English guides and study summaries from published literature.
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