Live prices from 17 SA suppliers, from R300.00, compared side by side so you never overpay.
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Compare 7 prices for DSIP. Cheapest: R350.00. Average: R624.29.
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Striata Labs
Best
DSIP 5mg |
R350.00 | R70.00/mg | In Stock | R150.00 |
Lab Tested
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DSIP 5mg |
R575.00 | R115.00/mg | In Stock | R95.00 |
Lab Tested
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DSIP 5mg |
R620.00 | R124.00/mg | In Stock | R170.00 |
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DSIP Pen |
R639.00 | R127.80/mg | In Stock | Free over R600 |
Lab Tested
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DSIP Pen |
R648.00 | R129.60/mg | In Stock | R150.00 |
Lab Tested
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DSIP Nasal |
R709.00 | R141.80/mg | In Stock | R185.00 |
Lab Tested
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DSIP 5mg |
R829.00 | R165.80/mg | In Stock | R250.00 |
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Delta Sleep-Inducing Peptide | Sleep & Stress Modulator
DSIP is a naturally occurring nonapeptide discovered in 1974 in rabbit brain. Originally isolated for sleep-promoting properties, it has diverse neuromodulatory effects including stress reduction, pain modulation, and endocrine regulation without traditional sedative effects.
Modulates multiple neurotransmitter systems including GABA enhancement, NMDA receptor interaction, and endogenous opioid system modulation. Also regulates hypothalamic-pituitary-adrenal axis for stress response.
WAGGDASGE
Tryptophan
Position 1
Alanine
Position 2
Glycine
Position 3
Glycine
Position 4
Aspartic Acid
Position 5
Alanine
Position 6
Serine
Position 7
Glycine
Position 8
Glutamic Acid
Position 9
Promotes delta wave sleep, the most restorative sleep phase for physical recovery.
Reduces sleep latency and nocturnal awakenings without morning grogginess.
Supports natural sleep cycles rather than forcing sedation like traditional sleep aids.
Helps regulate cortisol and stress response through HPA axis modulation.
Supports emotional balance without sedation.
May help reduce anxiety through neuromodulatory effects.
Significantly reduced pain levels in 6 of 7 patients with chronic pain conditions.
Helps manage withdrawal symptoms in alcohol and opioid-dependent patients.
Supports post-training recovery through enhanced sleep quality.
Subcutaneous injection is the standard route. Best taken 30-60 minutes before bedtime. Some prefer earlier evening dosing for gradual onset.
| Goal | Dose | Frequency | Route |
|---|---|---|---|
| Sleep enhancement | 100-200mcg | Once nightly | SubQ |
| Chronic pain support | 250-300mcg | Daily | SubQ or IV |
| Stress management | 150mcg | Evening | SubQ |
| Withdrawal support | 200-300mcg | Twice daily | IV preferred |
| Athletic recovery | 100-150mcg | Post-training | SubQ |
Intranasal spray offers convenient administration with limited stability data.
| Goal | Dose | Frequency | Route |
|---|---|---|---|
| Sleep induction | 200-300mcg | Once at bedtime | Nasal spray |
| Stress relief | 150-200mcg | Twice daily | Nasal spray |
| Neuroprotection | 300-400mcg | Daily | Nasal spray |
Both regulate sleep-wake cycles; complementary benefits.
DSIP enhances GABA - watch for excessive sedation.
Can combine for comprehensive stress management.
Complementary anxiolytic effects.
Different mechanisms; can optimize 24-hour function.
May modulate opioid receptors; requires professional supervision.
No direct interaction; DSIP may support natural GH release during sleep.
Both support circadian regulation and sleep quality.
Noticeable sleep pressure and easier sleep onset
Deeper sleep, fewer awakenings, vivid dreams possible
Improved morning refreshment, stable daytime energy
Cumulative stress reduction, mood improvements
Benefits may persist 1-2 weeks after stopping
Neuropeptide Research
Comprehensive review of DSIP's stress-protective mechanisms over four decades of research.
Drug Delivery Research
Enhanced intranasal delivery methods for improved bioavailability.
15-30 nmol for 6 consecutive nights improved objective sleep quality with higher sleep efficiency and shorter sleep latency compared to placebo.
25 nmol IV for 10 days significantly reduced pain levels in 6 of 7 patients with chronic pain conditions including migraine and tinnitus.
DSIP administration helped manage withdrawal symptoms in both alcohol and opioid-dependent patients over 5-10 days.
Single 25 nmol/kg IV dose showed 59% increase in total sleep time within 130 minutes; improved subsequent night sleep efficiency.
120mcg/kg nasal for 7 days enhanced motor recovery without significantly reducing infarct size.
Plain-English guides and study summaries from published literature.
Guides
7 min
DSIP is an emerging sleep research peptide linked to slow wave sleep, stress response and neuroendocrine signalling. The evidence is interesting, but mixed and still experimental.
Read article
Guides
6 min
DSIP is best known for sleep research, but its scientific interest extends to stress response, neuroendocrine signalling, mood and recovery. The evidence is emerging, so stronger claims need caution.
Read articleBe the first to know when prices drop on your favourite peptides
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