---
title: "PE-22-28 Research & Guides - Studies & Safety - PeptideSupermarket®"
description: "Plain-English research articles, study summaries and safety notes on PE-22-28 from published scientific literature."
url: "https://peptidesupermarket.co.za/research/peptide/pe-22-28"
site: "PeptideSupermarket®"
country: "South Africa"
---

[Home](https://peptidesupermarket.co.za) › Research

Research & Guides

# PE-22-28 research & guides

Plain-English guides, study summaries and safety notes from published scientific literature — **76 articles** and counting.

Reference-backed Updated regularly Zero medical advice

All content is for educational and research reference purposes only. It does not constitute medical advice, diagnosis, or treatment recommendations. [Read our full disclosure](https://peptidesupermarket.co.za/disclosure).

Library

## PE-22-28 articles

1 article available.

[All 76](https://peptidesupermarket.co.za/research/peptide/pe-22-28) [Guides 76](https://peptidesupermarket.co.za/research/peptide/pe-22-28?category=guides)

Guides 7 min

PE-22-28

### PE-22-28: TREK-1 Peptide Research for Mood and Brain Health

PE-22-28 is an emerging shortened Spadin analogue studied for TREK-1 potassium channel blockade, mood-related models and neuroplasticity. Human evidence remains limited.

18 Aug 2026 Read

[PE-22-28: TREK-1 Peptide Research for Mood and Brain Health](https://peptidesupermarket.co.za/research/pe-22-28-trek-1-peptide-research-for-mood-and-brain-health)

---

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