--- title: "Semax Peptide SA - Compare Prices from 27 Suppliers - PeptideSupermarket®" description: "Compare Semax prices from 27 SA suppliers, from R375.00. Find the cheapest deals, read reviews and save money." url: "https://peptidesupermarket.co.za/peptide/semax" site: "PeptideSupermarket®" country: "South Africa" --- [Home](https://peptidesupermarket.co.za) › [Peptides](https://peptidesupermarket.co.za/compare-peptide-prices-za) › Semax Search # Semax Price Comparison Live prices from 27 SA suppliers, from R375.00, compared side by side so you never overpay. [Neuropeptides & sleep research](https://peptidesupermarket.co.za/compare-peptide-prices-za) Prices checked 48 minutes ago We compare prices & may earn a commission. [Full disclosure](https://peptidesupermarket.co.za/disclosure). Best Price R375.00 Average R858.57 Highest R2,190.00 You Could Save 83% 28 results 10mg Compare 28 prices for Semax. Cheapest: R375.00. Average: R858.57. | Compare | Supplier | Price | Price / mg | Stock | Delivery | Quality | Coupon | Visit | | --- | --- | --- | --- | --- | --- | --- | --- | --- | | | [Neurovia](https://peptidesupermarket.co.za/suppliers/neurovia) Best Semax 10mg | R375.00 | R37.50/mg | In Stock | R250.00 | Lab Tested | — | Visit | | | [TrueForm](https://peptidesupermarket.co.za/suppliers/trueform) Semax 10mg | R400.00 | R40.00/mg | In Stock | Free over R4,000 | — | — | Visit | | | [Gander Peptides](https://peptidesupermarket.co.za/suppliers/gander-peptiodes) Semax 10mg | R439.00 | R43.90/mg | In Stock | R159.00 | Lab Tested | — | Visit | | | [Crono Pharm](https://peptidesupermarket.co.za/suppliers/chrono-pharm) Semax 10mg | R450.00 | R45.00/mg | In Stock | R150.00 | Lab Tested | — | Visit | | | [Buy Peptides](https://peptidesupermarket.co.za/suppliers/buy-peptides) Semax 10mg | R530.00 | R53.00/mg | In Stock | R250.00 | — | — | Visit | | | [JP Research](https://peptidesupermarket.co.za/suppliers/jp-research) Semax | R549.00 | R54.90/mg | Out of Stock | Free | Lab Tested | — | Visit | | | [Buy Peptides](https://peptidesupermarket.co.za/suppliers/buy-peptides) Semax Nasal | R600.00 | R60.00/mg | In Stock | R250.00 | — | — | Visit | | | [Crono Pharm](https://peptidesupermarket.co.za/suppliers/chrono-pharm) Semax Nasal | R620.00 | R62.00/mg | In Stock | R150.00 | Lab Tested | — | Visit | | | [Reschem](https://peptidesupermarket.co.za/suppliers/reschem) Semax Pen | R649.00 | R64.90/mg | In Stock | Free over R600 | Lab Tested | — | Visit | | | [Peptide Labs](https://peptidesupermarket.co.za/suppliers/peptide-labs) Semax 10mg | R650.00 | R65.00/mg | In Stock | R170.00 | — | — | Visit | | | [Grow Nova](https://peptidesupermarket.co.za/suppliers/grow-nova) Semax 10mg | R650.00 | R65.00/mg | In Stock | R170.00 | — | — | Visit | | | [Striata Labs](https://peptidesupermarket.co.za/suppliers/striata-labs) Semax 10mg | R650.00 | R65.00/mg | In Stock | R150.00 | Lab Tested | — | Visit | | | [ReGen-X](https://peptidesupermarket.co.za/suppliers/regen-x) Semax 10mg | R750.00 | R75.00/mg | In Stock | Free over R1,200 | — | — | Visit | | | [Peptide Warehouse](https://peptidesupermarket.co.za/suppliers/peptide-warehouse) Semax 10mg | R775.00 | R77.50/mg | In Stock | R95.00 | Lab Tested | — | Visit | | | [White Rabbit Labs](https://peptidesupermarket.co.za/suppliers/white-rabbit-labs) Semax 10mg | R780.00 | R78.00/mg | In Stock | R120.00 | — | — | Visit | | | [Pure Performance Labs](https://peptidesupermarket.co.za/suppliers/pure-performance-labs) Semax 10mg | R828.00 | R82.80/mg | In Stock | R250.00 | Lab Tested | — | Visit | | | [Biolabs Peptides](https://peptidesupermarket.co.za/suppliers/biolabs-peptides) Semax Nasal | R830.00 | R83.00/mg | In Stock | R185.00 | Lab Tested | — | Visit | | | [Grow Nova](https://peptidesupermarket.co.za/suppliers/grow-nova) Semax Nasal | R830.00 | R83.00/mg | In Stock | R170.00 | — | — | Visit | | | [Biolabs Peptides](https://peptidesupermarket.co.za/suppliers/biolabs-peptides) Semax 10mg | R950.00 | R95.00/mg | In Stock | R185.00 | Lab Tested | — | Visit | | | [Grow Nova](https://peptidesupermarket.co.za/suppliers/grow-nova) Semax | R950.00 | R95.00/mg | In Stock | R170.00 | — | — | Visit | | | [Kynex Bioscience](https://peptidesupermarket.co.za/suppliers/kynex-bioscience) Semax 10mg | R980.00 | R98.00/mg | In Stock | Free over R2,200 | Lab Tested | — | Visit | | | [Pure Peptides SA](https://peptidesupermarket.co.za/suppliers/pure-peptides-sa) Semax | R995.00 | R99.50/mg | In Stock | R200.00 | — | — | Visit | | | [BioPeptics](https://peptidesupermarket.co.za/suppliers/biopeptics) Semax 10mg | R1,000.00 | R100.00/mg | In Stock | R150.00 | — | — | Visit | | | [Oh My Health](https://peptidesupermarket.co.za/suppliers/oh-mynhealth) Semax Pen | R1,320.00 | R132.00/mg | In Stock | R250.00 | — | — | Visit | | | [Bio Muti](https://peptidesupermarket.co.za/suppliers/bio-muti) Semax 10mg | R1,380.00 | R138.00/mg | In Stock | R200.00 | — | — | Visit | Showing 25 of 28 listings Show more suppliers Loading More ways to compare Semax Different views of the same live SA pricing, tuned for how you like to shop. [Best Semax Prices Best prices ranked](https://peptidesupermarket.co.za/best-semax-prices) [Cheapest Semax Prices Cheapest suppliers compared](https://peptidesupermarket.co.za/cheapest-semax-prices) [Where to Buy Semax Full buyer's guide](https://peptidesupermarket.co.za/where-to-buy-semax) [Buy Semax Online SA Cheap Today's hottest deals](https://peptidesupermarket.co.za/buy-semax-online-za-cheap) [Semax Price Comparison Live price dashboard](https://peptidesupermarket.co.za/semax-price-comparison) [Semax SA Supplier Verified SA supplier directory](https://peptidesupermarket.co.za/semax-za-supplier) [Semax For Sale Browse listings for sale](https://peptidesupermarket.co.za/semax-for-sale) Compare another peptide Search PeptideSupermarket® compares prices but doesn't sell products. More All purchases are made directly from third-party suppliers; your relationship is solely with them. We accept no liability for the quality, purity, or legality of any products listed. We may earn a commission when you click through to a supplier and make a purchase. This does not affect pricing information displayed. By using this site you accept responsibility for ensuring purchases comply with applicable laws in your jurisdiction. [Read our full disclosure](https://peptidesupermarket.co.za/disclosure). ## Semax Profile Well Studied Synthetic ACTH Analog | Nootropic & Neuroprotective Peptide ### Overview Semax is a synthetic heptapeptide derived from adrenocorticotropic hormone (ACTH) fragment 4-10, originally developed in Russia for stroke recovery. It achieves enhanced CNS penetration through direct transport via olfactory epithelium and trigeminal nerves, bypassing the blood-brain barrier. ### Mechanism of Action Rapidly increases BDNF levels, modulates dopaminergic and serotonergic systems, and achieves direct brain delivery through olfactory transport with 0.093% blood-brain barrier penetration (vs 0.01% IV). ### Key Benefits - Rapid brain delivery via intranasal route - Rapidly increases BDNF levels - Extensive clinical research in Russia - Easy self-administration - Modulates dopamine and serotonin systems - Neuroprotective effects ### Quick Stats Typical Dose 300-600mcg per dose (up to 1000mcg for intensive use) Frequency 1-2x daily (morning recommended for cognitive boost) Cycle Duration 2-4 weeks on Storage Reconstituted: 2-8°C, use within recommended timeframe ## Molecular Information Molecular Weight 813.93 Da Length 7 amino acids Type ACTH(4-10) synthetic analog Half-Life 0.5-2 hours ### Amino Acid Sequence One-letter: `MEHFPGP` Met 1 Methionine Position 1 Glu 2 Glutamic Acid Position 2 His 3 Histidine Position 3 Phe 4 Phenylalanine Position 4 Pro 5 Proline Position 5 Gly 6 Glycine Position 6 Pro 7 Proline Position 7 N-terminus C-terminus Hydrophobic Polar Positive (+) Negative (-) Modified ### Modifications Enhanced stability synthetic analog ## Research Indications The following information is derived from published scientific literature and is provided for educational and research reference purposes only. It does not constitute medical advice, diagnosis, or treatment recommendations. These peptides are not approved for human use and are sold exclusively for in-vitro laboratory research. Cognitive Neuroprotection Neuroplasticity ## Dosing Protocols ### nasal Intranasal is the primary and most effective route, providing direct brain delivery through olfactory transport. Onset 15-30 minutes, peak 1-2 hours, duration 4-6 hours. | Goal | Dose | Frequency | Route | | --- | --- | --- | --- | | Cognitive enhancement | 300-600mcg | 1-2x daily | Intranasal spray/drops | | Intensive cognitive support | 600-900mcg | 2-3x daily | Intranasal | | Brain injury recovery | 900-1500mcg | 2-3x daily | Intranasal | #### Key Tips - Fastest and most effective route - Direct brain delivery (0.093% BBB penetration) - No injection required - Onset 15-30 minutes Reconstitution Instructions ### injectable Subcutaneous injection provides reliable dosing. Onset 30-60 minutes, peak 2-4 hours, duration 6-8 hours. | Goal | Dose | Frequency | Route | | --- | --- | --- | --- | | Research protocol | 500-750mcg | 1x daily | SubQ | | Intensive protocol | 750-1000mcg | 1-2x daily | SubQ | #### Key Tips - Reliable dosing - Longer duration than nasal Reconstitution Instructions ## Peptide Interactions #### NA-Semax-Amidate Avoid Do NOT use simultaneously. Choose one or the other - they are variants of the same peptide. #### Selank Synergistic Complementary anxiolytic effects; popular combination. #### BPC-157 Compatible Both support neuroplasticity through different mechanisms. #### TB-500 Compatible Comprehensive neuroprotection when combined. #### Stimulants Monitor May enhance stimulant effects - monitor carefully and reduce stimulant doses. #### MAO Inhibitors Monitor Theoretical monoamine system risk; use caution. ## What to Expect Days 1-3 Initial cognitive clarity and focus enhancement, possible mild nasal sensation Week 1 Improved attention span during demanding tasks Week 2-3 Enhanced memory consolidation, stable mood Week 4 Peak cognitive benefits with improved stress resilience and mental flexibility Post-cycle Gradual baseline return over 3-7 days; some benefits persist ## Side Effects & Safety #### Common Side Effects - Mild nasal discomfort (nasal route) - Possible nasal sensation upon administration #### Monitoring - Start with lowest effective dose (300mcg) to assess individual response - Avoid concurrent intranasal vasoconstrictors - Monitor for nasal irritation/bleeding - May enhance stimulant effects - reduce other stimulant doses #### Stop Signs - Severe nasal irritation, bleeding, or persistent congestion - Unusual anxiety, agitation, or sleep disturbances - Headaches worsening with use - Signs of allergic reaction (rash, breathing difficulty) - Significant blood pressure changes or heart palpitations #### Contraindications - Pregnancy or breastfeeding - Known peptide allergies - Do not exceed 4-week continuous use without medical supervision ## Quality Checklist #### Good Signs - Clear, colorless solution (nasal) - Proper concentration labeling as 0.1% or 1% Semax - Cold chain shipping with cold packs - Sterile packaging (sealed bottles/ampoules) - White lyophilized powder (injectable) - Complete dissolution in solution - Third-party testing (≥98% purity) #### Warning Signs - Nasal irritation potential - Injection site reactions (redness, swelling) #### Bad Signs - Crystallization or precipitation indicates degradation - Cloudy or colored solutions - Any visible particles ## Research & References ### Latest Research 2021 #### Anti-amyloid Properties in Alzheimer's Models ACS Chemical Neuroscience Demonstrated anti-amyloid properties with potential Alzheimer's applications. 2023 #### BDNF Enhancement and Neuroplasticity Neuroscience Research Reviews Updated review of BDNF enhancement mechanisms. 2024 #### Intranasal BBB Penetration Study Clinical Pharmacology Research Intranasal administration achieves 0.093% blood-brain barrier penetration versus 0.01% with intravenous. ### Key References 1. 1996 #### Cognitive Enhancement in Fatigued Workers Human study with 250-1000mcg intranasal single dose showed 71% accuracy on memory tests vs 41% in controls. 2. 2018 #### Stroke Recovery Clinical Trial 110 patients with ischemic stroke showed increased BDNF levels correlated with early rehabilitation when using Semax with conventional therapy. 3. 2018 #### fMRI Default Mode Network Study 24 healthy middle-aged participants showed increased fMRI default mode network activity relative to placebo. 4. 2014 #### Neuroprotective Effects in Brain Ischemia Rat focal ischemia model showed Semax affected expression of 96 genes related to immune and vascular systems. [Search PubMed for Semax](https://pubmed.ncbi.nlm.nih.gov/?term=%28%22Semax%22%20OR%20%22L-Prolyl-L-glutamyl-L-lysyl-L-glutamyl-L-tryptophyl-L-tryptophyl-L-tryptophyl-L-arginyl-L-prolyl-L-prolyl-L-glutamyl-L-lysyl-L-tryptophyl-L-lysyl-L-prolyl-L-tryptophyl-L-phenylalanine%22%20OR%20%22NA-Semax%22%29) Research Library ## Semax research & guides Plain-English guides and study summaries from published literature. [View all 2](https://peptidesupermarket.co.za/research/peptide/semax) ![Semax Peptide Guide: Cognitive Enhancement, BDNF and Research Use](https://peptidesupermarket.co.za/storage/1597/conversions/Semax-Image-Pepsup-thumbnail.jpg) Guides 6 min ### Semax Peptide Guide: Cognitive Enhancement, BDNF and Research Use Semax is a synthetic ACTH-derived heptapeptide studied for focus, memory, BDNF signalling and neuroprotection. This guide explains what the research discussion supports and where caution is needed. Read article [Semax Peptide Guide: Cognitive Enhancement, BDNF and Research Use](https://peptidesupermarket.co.za/research/semax-peptide-guide-cognitive-enhancement-bdnf-and-research-use) ![Semax peptide: brain-focused nootropic research guide](https://peptidesupermarket.co.za/storage/1385/conversions/Semax-Image-Pepsup-thumbnail.jpg) Guides 7 min ### Semax peptide: brain-focused nootropic research guide Semax is a synthetic ACTH-derived heptapeptide studied for BDNF signalling, memory, attention and neuroprotection. This guide explains what the research focus means and where the limits are. Read article [Semax peptide: brain-focused nootropic research guide](https://peptidesupermarket.co.za/research/semax-peptide-brain-focused-nootropic-research-guide) --- *Add `.md` to any page URL on peptidesupermarket.co.za for its Markdown version. Index of the site: https://peptidesupermarket.co.za/llms.txt - full text: https://peptidesupermarket.co.za/llms-full.txt.*