--- title: "PT-141 Peptide SA - Compare Prices from 28 Suppliers - PeptideSupermarket®" description: "Compare PT-141 prices from 28 SA suppliers, from R349.00. Find the cheapest deals, read reviews and save money." url: "https://peptidesupermarket.co.za/peptide/pt-141" site: "PeptideSupermarket®" country: "South Africa" --- [Home](https://peptidesupermarket.co.za) › [Peptides](https://peptidesupermarket.co.za/compare-peptide-prices-za) › PT-141 Search # PT-141 Price Comparison Live prices from 28 SA suppliers, from R349.00, compared side by side so you never overpay. [Melanocortins](https://peptidesupermarket.co.za/compare-peptide-prices-za) Prices checked 43 minutes ago We compare prices & may earn a commission. Includes a featured placement — not an endorsement. [Full disclosure](https://peptidesupermarket.co.za/disclosure). Best Price R349.00 Average R654.50 Highest R1,564.00 You Could Save 78% 38 results 10mg Featured Supplier [BioHack Peptides](https://peptidesupermarket.co.za/suppliers/biohack-peptides) ★★★★★ [4.9 reviews](https://peptidereview.co.uk/review/biohackpeptides.co.uk) PT-141 In Stock 10mg Lab Tested R550.00 FREE over R3,000 View Deal Compare 38 prices for PT-141. Cheapest: R349.00. Average: R654.50. | Compare | Supplier | Price | Price / mg | Stock | Delivery | Quality | Coupon | Visit | | --- | --- | --- | --- | --- | --- | --- | --- | --- | | | [JP Research](https://peptidesupermarket.co.za/suppliers/jp-research) Best PT-141 | R349.00 | R34.90/mg | In Stock | Free | Lab Tested | — | Visit | | | [Grow Nova](https://peptidesupermarket.co.za/suppliers/grow-nova) PT-141 10mg | R350.00 | R35.00/mg | In Stock | R170.00 | — | — | Visit | | | [Helix Collective](https://peptidesupermarket.co.za/suppliers/helix-collective) PT-141 10mg | R363.00 | R36.30/mg | In Stock | R170.00 | — | — | Visit | | | [Crono Pharm](https://peptidesupermarket.co.za/suppliers/chrono-pharm) PT-141 10mg | R380.00 | R38.00/mg | In Stock | R150.00 | Lab Tested | — | Visit | | | [TrueForm](https://peptidesupermarket.co.za/suppliers/trueform) PT-141 10mg | R400.00 | R40.00/mg | In Stock | Free over R4,000 | — | — | Visit | | | [Lipo Lab](https://peptidesupermarket.co.za/suppliers/lipo-lab) PT-141 10mg | R410.00 | R41.00/mg | In Stock | R250.00 | Lab Tested | — | Unavailable | | | [White Rabbit Labs](https://peptidesupermarket.co.za/suppliers/white-rabbit-labs) PT-141 10mg | R450.00 | R45.00/mg | In Stock | R120.00 | — | — | Visit | | | [Impact Nutrition](https://peptidesupermarket.co.za/suppliers/impact-nutrition) PT-141 10mg | R459.00 | R45.90/mg | In Stock | R250.00 | — | — | Visit | | | [Grow Nova](https://peptidesupermarket.co.za/suppliers/grow-nova) PT-141 10mg | R460.00 | R46.00/mg | In Stock | R170.00 | — | — | Visit | | | [Grow Nova](https://peptidesupermarket.co.za/suppliers/grow-nova) PT-141 10mg | R490.00 | R49.00/mg | In Stock | R170.00 | — | — | Visit | | | [Atlas Nutrition](https://peptidesupermarket.co.za/suppliers/atlas-nutrition) PT-141 10mg | R500.00 | R50.00/mg | In Stock | Free over R2,000 | — | — | Visit | | | [Grow Nova](https://peptidesupermarket.co.za/suppliers/grow-nova) PT-141 10mg | R500.00 | R50.00/mg | In Stock | R170.00 | — | — | Visit | | | [Ignite Muscle](https://peptidesupermarket.co.za/suppliers/ignite-muscle) PT-141 10mg | R500.00 | R50.00/mg | In Stock | R250.00 | — | — | Unavailable | | | [Crono Pharm](https://peptidesupermarket.co.za/suppliers/chrono-pharm) PT-141 Nasal | R520.00 | R52.00/mg | In Stock | R150.00 | Lab Tested | — | Visit | | | [Apex Genetics](https://peptidesupermarket.co.za/suppliers/apex-genetics) PT-141 | R525.00 | R52.50/mg | In Stock | R99.00 | Lab Tested | — | Visit | | | [Pure Peptides SA](https://peptidesupermarket.co.za/suppliers/pure-peptides-sa) PT-141 | R540.00 | R54.00/mg | In Stock | R200.00 | — | — | Visit | | | [Peptide Warehouse](https://peptidesupermarket.co.za/suppliers/peptide-warehouse) PT-141 10mg | R550.00 | R55.00/mg | In Stock | R95.00 | Lab Tested | — | Visit | | | [Biolabs Peptides](https://peptidesupermarket.co.za/suppliers/biolabs-peptides) PT-141 10mg | R583.00 | R58.30/mg | Out of Stock | R185.00 | Lab Tested | — | Visit | | | [Grow Nova](https://peptidesupermarket.co.za/suppliers/grow-nova) PT-141 10mg | R583.00 | R58.30/mg | In Stock | R170.00 | — | — | Visit | | | [Peptide Pen](https://peptidesupermarket.co.za/suppliers/peptide-pen) PT-141 10mg | R605.00 | R60.50/mg | In Stock | R250.00 | — | — | Visit | | | [All Peptides](https://peptidesupermarket.co.za/suppliers/all-peptides) PT-141 10mg | R625.00 | R62.50/mg | In Stock | R100.00 | — | — | Visit | | | [Bio Harmony Group](https://peptidesupermarket.co.za/suppliers/bio-harmony-group) PT-141 Pen | R628.00 | R62.80/mg | In Stock | R150.00 | Lab Tested | — | Visit | | | [SA Peptides](https://peptidesupermarket.co.za/suppliers/sa-peptides) PT-141 10mg | R650.00 | R65.00/mg | In Stock | R140.00 | — | — | Visit | | | [Buy Peptides](https://peptidesupermarket.co.za/suppliers/buy-peptides) PT-141 10mg | R650.00 | R65.00/mg | In Stock | R250.00 | — | — | Visit | | | [Pure Performance Labs](https://peptidesupermarket.co.za/suppliers/pure-performance-labs) PT-141 10mg | R665.85 | R66.59/mg | In Stock | R250.00 | Lab Tested | — | Visit | Showing 25 of 37 listings Show more suppliers Loading More ways to compare PT-141 Different views of the same live SA pricing, tuned for how you like to shop. [Best PT-141 Prices Best prices ranked](https://peptidesupermarket.co.za/best-pt-141-prices) [Cheapest PT-141 Prices Cheapest suppliers compared](https://peptidesupermarket.co.za/cheapest-pt-141-prices) [Where to Buy PT-141 Full buyer's guide](https://peptidesupermarket.co.za/where-to-buy-pt-141) [Buy PT-141 Online SA Cheap Today's hottest deals](https://peptidesupermarket.co.za/buy-pt-141-online-za-cheap) [PT-141 Price Comparison Live price dashboard](https://peptidesupermarket.co.za/pt-141-price-comparison) [PT-141 SA Supplier Verified SA supplier directory](https://peptidesupermarket.co.za/pt-141-za-supplier) [PT-141 For Sale Browse listings for sale](https://peptidesupermarket.co.za/pt-141-for-sale) Compare another peptide Search PeptideSupermarket® compares prices but doesn't sell products. More All purchases are made directly from third-party suppliers; your relationship is solely with them. We accept no liability for the quality, purity, or legality of any products listed. We may earn a commission when you click through to a supplier and make a purchase. This does not affect pricing information displayed. By using this site you accept responsibility for ensuring purchases comply with applicable laws in your jurisdiction. [Read our full disclosure](https://peptidesupermarket.co.za/disclosure). ## PT-141 Profile Fda Approved FDA Approved Melanocortin Receptor Agonist | Sexual Dysfunction Treatment ### Overview FDA-approved melanocortin receptor agonist for treatment of hypoactive sexual desire disorder (HSDD) in premenopausal women. Works centrally in the nervous system to trigger sexual arousal pathways independent of vascular mechanisms, unlike traditional ED medications. ### Mechanism of Action Selectively activates melanocortin receptors (MC3R/MC4R) in the central nervous system, triggering sexual arousal pathways independent of peripheral vascular mechanisms. Works within 45 minutes with effects lasting 6-12 hours. ### Key Benefits - FDA-approved pharmaceutical route - Predictable absorption profile - Effective for both male and female sexual dysfunction - Works within 45 minutes - Effective in PDE5 inhibitor-resistant cases - Central mechanism (not dependent on blood flow) ### Quick Stats Typical Dose Women: 1.75mg (FDA-approved); Men: 1-2mg; Start 0.5mg test dose for tolerance Frequency As needed before sexual activity; max 1 dose per 24 hours Cycle Duration Use as needed for sexual enhancement Storage Refrigerate at 2-8°C, use reconstituted solution within 30 days ## Molecular Information Type Melanocortin receptor agonist Half-Life ~2.7 hours ### Modifications Selective MC3R/MC4R activation ## Research Indications The following information is derived from published scientific literature and is provided for educational and research reference purposes only. It does not constitute medical advice, diagnosis, or treatment recommendations. These peptides are not approved for human use and are sold exclusively for in-vitro laboratory research. Sexual Health Quality of Life ## Dosing Protocols ### injectable Subcutaneous injection is the FDA-approved route. Administered 45-60 minutes before anticipated sexual activity. | Goal | Dose | Frequency | Route | | --- | --- | --- | --- | | Female HSDD (FDA-approved) | 1.75mg | As needed, max 1 dose/24hr | SubQ | | Male Erectile Dysfunction | 1-2mg | As needed, 45-60min before activity | SubQ | | Female Arousal Disorder | 0.75-1.25mg | As needed, max 1 dose/24hr | SubQ | | Low Starting Dose | 0.5mg | Test dose for tolerance assessment | SubQ | #### Key Tips - Abdomen 2 inches from navel or upper thigh - Onset 45-60 minutes - Peak effects 2-4 hours - Duration 6-12 hours Reconstitution Instructions ### nasal Intranasal spray with faster onset (30-45 minutes). Limited clinical data compared to injectable. | Goal | Dose | Frequency | Route | | --- | --- | --- | --- | | Male ED - Standard | 1.5-2mg | As needed, 30-45min before | Nasal | | Female Sexual Dysfunction | 1-1.5mg | As needed, max 1 dose/24hr | Nasal | #### Key Tips - Non-invasive administration - Faster onset than injectable ## Peptide Interactions #### Sildenafil/Tadalafil Monitor PT-141 works centrally; PDE5 inhibitors work peripherally - monitor for additive BP effects. #### Melanotan II Monitor Both are melanocortin agonists; combining risks excessive activation and side effects. #### Blood Pressure Medications Monitor PT-141 can transiently lower blood pressure - monitor closely. #### Alcohol Monitor Both lower BP and cause flushing - limit intake to avoid excessive hypotension. #### Nitrates Avoid Risk of severe hypotension - contraindicated with heart condition medications. #### BPC-157 Compatible Different mechanisms; no known interactions. #### Testosterone Synergistic May work synergistically for sexual dysfunction through different pathways. #### Kisspeptin Monitor Different pathways (melanocortin vs GnRH) - no receptor overlap but monitor BP effects. ## What to Expect 0-30 minutes Mild nausea or facial flushing possible 45-90 minutes Onset of effects - increased arousal and desire 2-4 hours Peak effects - enhanced sexual response 6-12 hours Gradual diminishment of effects ## Side Effects & Safety #### Common Side Effects - Nausea (40%) - Flushing (20%) - Headache (11%) - Injection site reactions #### Monitoring - Blood pressure monitoring recommended - Take anti-nausea medication 30 minutes prior if prone to nausea - Avoid alcohol to minimize BP effects #### Stop Signs - Severe or persistent nausea/vomiting - Significant blood pressure drop or dizziness - Chest pain or irregular heartbeat - Severe headache or vision changes - Prolonged erection exceeding 4 hours #### Contraindications - Uncontrolled hypertension - Cardiovascular disease - Use of nitrate medications - Pregnancy or breastfeeding ## Quality Checklist #### Good Signs - FDA-approved pharmaceutical grade (Vyleesi) from licensed pharmacy - White crystalline powder (pure PT-141) - Clear solution when reconstituted - Proper labeling with concentration and purity #### Warning Signs - Compounded versions - ensure pharmacy is licensed and follows USP standards #### Bad Signs - Colored or oily appearance indicating impurities or degradation - Cloudy solution after reconstitution - Unknown source without quality documentation ## Research & References ### Latest Research December 2024 #### Long-term Safety Profile of Bremelanotide in Clinical Practice Journal of Sexual Medicine Real-world data of 10,000+ prescriptions shows consistent safety profile. October 2024 #### PT-141 Efficacy in Treatment-Resistant Sexual Dysfunction International Journal of Impotence Research Demonstrates effectiveness in patients who failed traditional ED medications. ### Key References 1. 2019 #### FDA Approval Trial for HSDD Phase 3 trials with 1.75mg subcutaneous in premenopausal women showed 24.5% improvement vs 17.2% placebo, achieving statistical significance. 2. 2017 #### Male Erectile Dysfunction Clinical Trial 1-20mg intranasal showed dose-dependent erectile response, effective including in PDE5 inhibitor-resistant cases via CNS pathways. 3. 2016 #### Mechanism of Action Study In vitro and animal studies confirmed selective MC3R/MC4R binding activating sexual arousal without peripheral vasodilation. [Search PubMed for PT-141](https://pubmed.ncbi.nlm.nih.gov/?term=%28%22PT-141%22%20OR%20%22Bremelanotide%22%20OR%20%22Vyleesi%22%29) Research Library ## PT-141 research & guides Plain-English guides and study summaries from published literature. [View all 1](https://peptidesupermarket.co.za/research/peptide/pt-141) ![PT-141 Guide: Melanocortin Peptide for Sexual Desire Research](https://peptidesupermarket.co.za/storage/1416/conversions/PT-141-PEPSUPSA-Image-thumbnail.jpg) Guides 8 min ### PT-141 Guide: Melanocortin Peptide for Sexual Desire Research PT-141, also known as bremelanotide, is a melanocortin receptor agonist studied for sexual desire and arousal pathways, with FDA approval for a narrow HSDD indication in premenopausal women. Read article [PT-141 Guide: Melanocortin Peptide for Sexual Desire Research](https://peptidesupermarket.co.za/research/pt-141-guide-melanocortin-peptide-for-sexual-desire-research) --- *Add `.md` to any page URL on peptidesupermarket.co.za for its Markdown version. Index of the site: https://peptidesupermarket.co.za/llms.txt - full text: https://peptidesupermarket.co.za/llms-full.txt.*