---
title: "Pinealon Peptide SA - Compare Prices from 7 Suppliers - PeptideSupermarket®"
description: "Compare Pinealon prices from 7 SA suppliers, from R250.00. Find the cheapest deals, read reviews and save money."
url: "https://peptidesupermarket.co.za/peptide/pinealon"
site: "PeptideSupermarket®"
country: "South Africa"
---

[Home](https://peptidesupermarket.co.za) › [Peptides](https://peptidesupermarket.co.za/compare-peptide-prices-za) › Pinealon Search

# Pinealon Price Comparison

Live prices from 7 SA suppliers, from R250.00, compared side by side so you never overpay.

[Skin & cellular longevity research](https://peptidesupermarket.co.za/compare-peptide-prices-za) Prices checked 48 minutes ago

We compare prices & may earn a commission. [Full disclosure](https://peptidesupermarket.co.za/disclosure).

Best Price R710.00

Average R808.75

Highest R900.00

You Could Save 21%

4 results 20mg

Compare 4 prices for Pinealon. Cheapest: R710.00. Average: R808.75.

| Compare | Supplier | Price | Price / mg | Stock | Delivery | Quality | Coupon | Visit |
| --- | --- | --- | --- | --- | --- | --- | --- | --- |
| | [White Rabbit Labs](https://peptidesupermarket.co.za/suppliers/white-rabbit-labs) Best Pinealon 20mg | R710.00 | R35.50/mg | In Stock | R120.00 | — | — | Visit |
| | [Peptide Warehouse](https://peptidesupermarket.co.za/suppliers/peptide-warehouse) Pinealon 20mg | R725.00 | R36.25/mg | In Stock | R95.00 | Lab Tested | — | Visit |
| | [SA Peptides](https://peptidesupermarket.co.za/suppliers/sa-peptides) Pinealon 20mg | R900.00 | R45.00/mg | In Stock | R140.00 | — | — | Visit |
| | [Buy Peptides](https://peptidesupermarket.co.za/suppliers/buy-peptides) Pinealon 20mg | R900.00 | R45.00/mg | In Stock | R250.00 | — | — | Visit |

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## Pinealon Profile

Well Studied

Synthetic Tripeptide | Neuroprotection & Cognitive Enhancement

### Overview

Developed in Russia, Pinealon demonstrates unique DNA-interaction for neuroprotection and cognitive enhancement. Benefits traumatic brain injury recovery and age-related cognitive decline with excellent safety profile.

### Mechanism of Action

Penetrates nuclear membranes to directly interact with DNA, modulates gene expression via histone H1.3 binding and MAPK/ERK pathway activation.

### Key Benefits

- Direct DNA interaction
- Neuroprotection
- Cognitive enhancement
- Excellent safety profile
- 40+ years of clinical use in Russia

### Quick Stats

Typical Dose

Injectable: 5mg daily or 100-300mcg daily; Oral: 0.2mg twice daily

Frequency

Injectable: daily for 20 days; Oral: morning and afternoon on empty stomach

Cycle Duration

20 days per cycle

Storage

Refrigerate at 2-8°C, use within 30 days after reconstitution

## Molecular Information

Molecular Weight

418.4 Da

Length

3 amino acids

Type

Tripeptide

Half-Life

Not established

### Amino Acid Sequence

One-letter: `ED?`

Glu

1

Glutamic Acid

Position 1

Asp

2

Aspartic Acid

Position 2

Arg

3

Arg (EDR)

Position 3

N-terminus C-terminus

Hydrophobic

Polar

Positive (+)

Negative (-)

Modified

### Modifications

Synthetic bioregulator with direct DNA interaction capabilities

## Research Indications

The following information is derived from published scientific literature and is provided for educational and research reference purposes only. It does not constitute medical advice, diagnosis, or treatment recommendations. These peptides are not approved for human use and are sold exclusively for in-vitro laboratory research.

Neuroprotection Cognitive Anti-Aging

## Dosing Protocols

### injectable

Highest bioavailability, direct systemic delivery, established clinical protocols.

| Goal | Dose | Frequency | Route |
| --- | --- | --- | --- |
| Neuroprotection | 5mg daily | Once daily | SubQ |
| Cognitive Enhancement | 100-300mcg | Daily or every other day | SubQ |
| Anti-aging | 5mg | 20 days, 2-3x yearly | SubQ |

#### Key Tips

- Highest bioavailability
- Direct systemic delivery
- Established clinical protocols

Reconstitution Instructions

### oral

Convenient, proven clinical efficacy. Ultra-short peptide structure survives gastric acid.

| Goal | Dose | Frequency | Route |
| --- | --- | --- | --- |
| Cognitive Enhancement | 0.2mg twice daily | Morning and afternoon | Empty stomach |
| Sleep Support | 200mcg | Daily | Oral |

#### Key Tips

- Convenient administration
- 3-amino acid structure achieves systemic absorption
- Proven clinical efficacy

### nasal

Theoretical nose-to-brain delivery, potential rapid CNS access. Limited data available.

#### Key Tips

- Potential direct brain access
- Non-invasive
- Requires further research

## Peptide Interactions

#### Epitalon

Synergistic

Enhanced neuroprotection through complementary telomerase activation pathways.

#### Cortexin

Synergistic

Synergistic cognitive recovery in stroke patients through brain region targeting.

#### Thymalin

Compatible

Safe combination supporting neural-immune axis optimization.

#### Melatonin

Monitor

Monitor sleep patterns; Pinealon stimulates endogenous serotonin production.

#### BPC-157

Compatible

Different mechanisms with no known interactions.

#### NAD+

Compatible

Complementary anti-aging mechanisms.

## What to Expect

Week 1-2

Improved mental clarity and focus

Week 2-3

Enhanced cognitive processing and memory

Week 3-4

Peak neuroprotective and anti-aging benefits

## Side Effects & Safety

#### Common Side Effects

- Minimal injection site reactions
- Mild gastrointestinal adjustment
- Occasional headache
- Fatigue

#### Monitoring

- Medical supervision recommended
- Rotate injection sites
- Use sterile technique

#### Stop Signs

- Severe headaches or mood changes
- Persistent injection site reactions
- Signs of infection at injection site
- Unusual neurological symptoms
- Allergic reactions

#### Contraindications

- Pregnancy
- Lactation

## Quality Checklist

#### Good Signs

- White crystalline powder; proper freeze-drying indicated
- Clear reconstituted solution; no particles or cloudiness
- Pharmaceutical packaging with batch numbers from reputable sources

#### Warning Signs

- Ensure distinction between research (lab only) and pharmaceutical (human use) grade

#### Bad Signs

- Discolored powder (yellow or brown) indicates degradation from heat or moisture
- Cloudy solution indicates contamination

## Research & References

### Key References

1. 2015

#### Human Clinical Trial - Post-Traumatic Cerebrasthenia

72 patients aged 30-74; 0.2mg twice daily; 20-30 days. Improved memory, reduced headache severity, and enhanced emotional stability compared to controls.
2. 2015

#### Aging Study - Polymorbidity Patients

32 patients aged 41-83; variable dosing; 30 days. Significant improvements in biological aging biomarkers with anabolic effects.
3. 2020

#### Diabetic Rat Model - Spatial Learning

100 ng/kg optimal dose; 14 days. Enhanced NMDA receptor expression in hippocampus with neuroplasticity improvements.
4. 2021

#### 5xFAD Alzheimer's Mouse Model

400 μg/kg IP daily; 28 days. Prevention of dendritic spine loss through MAPK/ERK pathway modulation.

[Search PubMed for Pinealon](https://pubmed.ncbi.nlm.nih.gov/?term=%28%22Pinealon%22%20OR%20%22EDR%22%20OR%20%22Glu-Asp-Arg%22%20OR%20%22Cerluten%22%29)

Research Library

## Pinealon research & guides

Plain-English guides and study summaries from published literature.

[View all 1](https://peptidesupermarket.co.za/research/peptide/pinealon)

![Pinealon: Sleep, Brain Fog and the Research Behind the EDR Peptide](https://peptidesupermarket.co.za/storage/1497/conversions/Pinealon-PEPSUPSA-Images-thumbnail.jpg) Guides 7 min

### Pinealon: Sleep, Brain Fog and the Research Behind the EDR Peptide

Pinealon, also known as EDR, is a synthetic tripeptide studied for neuroprotection, cognitive resilience and ageing-related brain health. The evidence is interesting, but still needs careful interpretation.

Read article

[Pinealon: Sleep, Brain Fog and the Research Behind the EDR Peptide](https://peptidesupermarket.co.za/research/pinealon-sleep-brain-fog-and-the-research-behind-the-edr-peptide)

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