--- title: "Humanin Peptide SA - Compare Prices from 2 Suppliers - PeptideSupermarket®" description: "Compare Humanin prices from 2 SA suppliers, from R1,050.00. Find the cheapest deals, read reviews and save money." url: "https://peptidesupermarket.co.za/peptide/humanin" site: "PeptideSupermarket®" country: "South Africa" --- [Home](https://peptidesupermarket.co.za) › [Peptides](https://peptidesupermarket.co.za/compare-peptide-prices-za) › Humanin Search # Humanin Price Comparison Live prices from 2 SA suppliers, from R1,050.00, compared side by side so you never overpay. [Skin & cellular longevity research](https://peptidesupermarket.co.za/compare-peptide-prices-za) Prices checked 53 minutes ago We compare prices & may earn a commission. [Full disclosure](https://peptidesupermarket.co.za/disclosure). Best Price R1,050.00 Average R1,300.00 Highest R1,550.00 You Could Save 32% 2 results 10mg Compare 2 prices for Humanin. Cheapest: R1,050.00. Average: R1,300.00. | Compare | Supplier | Price | Price / mg | Stock | Delivery | Quality | Coupon | Visit | | --- | --- | --- | --- | --- | --- | --- | --- | --- | | | [Buy Peptides](https://peptidesupermarket.co.za/suppliers/buy-peptides) Best Humanin 10mg | R1,050.00 | R105.00/mg | Out of Stock | R250.00 | — | — | Visit | | | [White Rabbit Labs](https://peptidesupermarket.co.za/suppliers/white-rabbit-labs) Humanin 10mg | R1,550.00 | R155.00/mg | In Stock | R120.00 | — | — | Visit | More ways to compare Humanin Different views of the same live SA pricing, tuned for how you like to shop. [Best Humanin Prices Best prices ranked](https://peptidesupermarket.co.za/best-humanin-prices) [Cheapest Humanin Prices Cheapest suppliers compared](https://peptidesupermarket.co.za/cheapest-humanin-prices) [Where to Buy Humanin Full buyer's guide](https://peptidesupermarket.co.za/where-to-buy-humanin) [Buy Humanin Online SA Cheap Today's hottest deals](https://peptidesupermarket.co.za/buy-humanin-online-za-cheap) [Humanin Price Comparison Live price dashboard](https://peptidesupermarket.co.za/humanin-price-comparison) [Humanin SA Supplier Verified SA supplier directory](https://peptidesupermarket.co.za/humanin-za-supplier) [Humanin For Sale Browse listings for sale](https://peptidesupermarket.co.za/humanin-for-sale) Compare another peptide Search PeptideSupermarket® compares prices but doesn't sell products. More All purchases are made directly from third-party suppliers; your relationship is solely with them. We accept no liability for the quality, purity, or legality of any products listed. We may earn a commission when you click through to a supplier and make a purchase. This does not affect pricing information displayed. By using this site you accept responsibility for ensuring purchases comply with applicable laws in your jurisdiction. [Read our full disclosure](https://peptidesupermarket.co.za/disclosure). ## Humanin Profile Moderate Research Mitochondria-Derived Peptide | HN ### Overview Humanin was the first mitochondria-derived peptide (MDP) discovered, originally cloned from the occipital lobe of an Alzheimer's patient. It is a 24-amino acid peptide encoded from the 16S rRNA region of mitochondrial DNA with potent neuroprotective, cytoprotective, and anti-apoptotic properties. Research shows humanin levels decline with age but remain stable in long-lived species like naked mole-rats, and offspring of centenarians have significantly higher humanin levels. ### Mechanism of Action Humanin exerts its effects through multiple mechanisms. It interacts with cell surface receptors including FPRL1 and CNTFR, activating PI3K/AKT signaling pathways that promote cell survival. It blocks pro-apoptotic proteins like Bax, reduces beta-amyloid toxicity in neurons, protects against oxidative stress, and promotes mitochondrial biogenesis. These actions support healthy cellular aging at a fundamental level. ### Key Benefits - Potent neuroprotection against Alzheimer's and Parkinson's pathology - Extended lifespan in animal models (C. elegans) - Improved metabolic healthspan parameters - Reduced inflammatory markers - Cytoprotective effects across multiple cell types - Anti-apoptotic activity - Mitochondrial optimization and biogenesis - Protection against oxidative stress ### Quick Stats Typical Dose 1-5 mg per injection (0.5-2 mg for HNG analog) Frequency 2-3 times weekly for sustained mitochondrial support Cycle Duration 8-12 weeks Storage Lyophilized: Room temperature. Reconstituted: 2-8°C, protect from light ## Molecular Information Molecular Weight 2,687 Da Length 24 amino acids Type Mitochondria-derived peptide Half-Life ~30 minutes (mice), >4 hours (rats) ### Amino Acid Sequence One-letter: `MAPRGFSCLLLLTSEIDLPVKRRA` Met 1 Methionine Position 1 Ala 2 Alanine Position 2 Pro 3 Proline Position 3 Arg 4 Arginine Position 4 Gly 5 Glycine Position 5 Phe 6 Phenylalanine Position 6 Ser 7 Serine Position 7 Cys 8 Cysteine Position 8 Leu 9 Leucine Position 9 Leu 10 Leucine Position 10 Leu 11 Leucine Position 11 Leu 12 Leucine Position 12 Thr 13 Threonine Position 13 Ser 14 Serine Position 14 Glu 15 Glutamic Acid Position 15 Ile 16 Isoleucine Position 16 Asp 17 Aspartic Acid Position 17 Leu 18 Leucine Position 18 Pro 19 Proline Position 19 Val 20 Valine Position 20 Lys 21 Lysine Position 21 Arg 22 Arginine Position 22 Arg 23 Arginine Position 23 Ala 24 Alanine Position 24 N-terminus C-terminus Hydrophobic Polar Positive (+) Negative (-) Modified ## Research Indications The following information is derived from published scientific literature and is provided for educational and research reference purposes only. It does not constitute medical advice, diagnosis, or treatment recommendations. These peptides are not approved for human use and are sold exclusively for in-vitro laboratory research. Neuroprotection Longevity Cellular Protection ## Dosing Protocols ### injectable Subcutaneous or intravenous injection. Benefits are slow-building and cellular, typically felt over weeks to months as the peptide supports mitochondria and reduces oxidative stress. The more potent analog HNG (glycine substitution at position 14) is 1000-fold more potent than native humanin. | Goal | Dose | Frequency | Route | | --- | --- | --- | --- | | Neuroprotection | 1-5 mg | 2-3x weekly | SubQ | | Longevity/Anti-aging | 1-3 mg | 2x weekly | SubQ | | HNG analog | 0.5-2 mg | 2x weekly | SubQ | #### Key Tips - Effects are slow-building over weeks/months - Works at the cellular/mitochondrial level - Detectable up to 12 hours post-administration - HNG analog is 1000x more potent Reconstitution Instructions ## Peptide Interactions #### MOTS-c Synergistic Both are mitochondria-derived peptides with complementary longevity and metabolic benefits. #### SS-31 Synergistic Both target mitochondrial function; may have additive benefits for cellular health. #### Epitalon Compatible Different mechanisms; can be combined in longevity protocols. #### NAD+ Synergistic Both support mitochondrial function and healthy aging. ## What to Expect Week 1-2 Subtle; peptide begins working at cellular level Week 2-4 Improved energy and reduced fatigue may begin Week 4-8 Enhanced cellular resilience and stress response Week 8-12 Cumulative benefits in mitochondrial function and healthspan markers Long-term Potential longevity and neuroprotective benefits ## Side Effects & Safety #### Common Side Effects - Injection site reactions - Mild fatigue initially - Headache (rare) #### Monitoring - Limited human clinical data available - Research peptide - medical supervision recommended #### Stop Signs - Signs of allergic reaction - Unusual persistent symptoms #### Contraindications - Active cancer (theoretical concern with anti-apoptotic effects) - Pregnancy or breastfeeding - Hypersensitivity to peptide components ## Quality Checklist #### Good Signs - White to off-white lyophilized powder - Clear solution after reconstitution - Intact vacuum seal #### Warning Signs - Slight clumping that dissolves easily #### Bad Signs - Discolored powder - Cloudy or particulate solution - Broken seal ## Research & References ### Key References 1. 2020 #### The mitochondrial derived peptide humanin is a regulator of lifespan and healthspan Aging Humanin overexpression extends lifespan in C. elegans; HNG treatment improves metabolic healthspan in middle-aged mice; levels higher in centenarian offspring. 2. 2023 #### Neuroprotective Action of Humanin and Humanin Analogues Biology (MDPI) Comprehensive review of humanin's neuroprotective effects in Alzheimer's and Parkinson's disease models. 3. 2022 #### Mitochondria-derived peptides in aging and healthspan Journal of Clinical Investigation Review of mitochondria-derived peptides including humanin and their roles in aging and metabolic health. 4. 2001 #### Original Discovery of Humanin Proceedings of the National Academy of Sciences Hashimoto et al. cloned humanin from Alzheimer's patient brain; demonstrated protection against amyloid-β toxicity. 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