--- title: "Dihexa Peptide SA - Compare Prices from 2 Suppliers - PeptideSupermarket®" description: "Compare Dihexa prices from 2 SA suppliers, from R550.00. Find the cheapest deals, read reviews and save money." url: "https://peptidesupermarket.co.za/peptide/dihexa" site: "PeptideSupermarket®" country: "South Africa" --- [Home](https://peptidesupermarket.co.za) › [Peptides](https://peptidesupermarket.co.za/compare-peptide-prices-za) › Dihexa Search # Dihexa Price Comparison Live prices from 2 SA suppliers, from R550.00, compared side by side so you never overpay. [Neuropeptides & sleep research](https://peptidesupermarket.co.za/compare-peptide-prices-za) Prices checked 1 hour ago We compare prices & may earn a commission. [Full disclosure](https://peptidesupermarket.co.za/disclosure). Best Price R550.00 Average R725.00 Highest R900.00 You Could Save 39% 2 results 10mg Compare 2 prices for Dihexa. Cheapest: R550.00. Average: R725.00. | Compare | Supplier | Price | Price / mg | Stock | Delivery | Quality | Coupon | Visit | | --- | --- | --- | --- | --- | --- | --- | --- | --- | | | [Crono Pharm](https://peptidesupermarket.co.za/suppliers/chrono-pharm) Best Dihexa | R550.00 | R55.00/mg | In Stock | R150.00 | Lab Tested | — | Visit | | | [Buy Peptides](https://peptidesupermarket.co.za/suppliers/buy-peptides) Dihexa 10mg | R900.00 | R90.00/mg | In Stock | R250.00 | — | — | Visit | More ways to compare Dihexa Different views of the same live SA pricing, tuned for how you like to shop. [Best Dihexa Prices Best prices ranked](https://peptidesupermarket.co.za/best-dihexa-prices) [Cheapest Dihexa Prices Cheapest suppliers compared](https://peptidesupermarket.co.za/cheapest-dihexa-prices) [Where to Buy Dihexa Full buyer's guide](https://peptidesupermarket.co.za/where-to-buy-dihexa) [Buy Dihexa Online SA Cheap Today's hottest deals](https://peptidesupermarket.co.za/buy-dihexa-online-za-cheap) [Dihexa Price Comparison Live price dashboard](https://peptidesupermarket.co.za/dihexa-price-comparison) [Dihexa SA Supplier Verified SA supplier directory](https://peptidesupermarket.co.za/dihexa-za-supplier) [Dihexa For Sale Browse listings for sale](https://peptidesupermarket.co.za/dihexa-for-sale) Compare another peptide Search PeptideSupermarket® compares prices but doesn't sell products. More All purchases are made directly from third-party suppliers; your relationship is solely with them. We accept no liability for the quality, purity, or legality of any products listed. We may earn a commission when you click through to a supplier and make a purchase. This does not affect pricing information displayed. By using this site you accept responsibility for ensuring purchases comply with applicable laws in your jurisdiction. [Read our full disclosure](https://peptidesupermarket.co.za/disclosure). ## Dihexa Profile Emerging Synaptogenic Peptide | Cognitive Enhancement ### Overview Dihexa is a synthetic oligopeptide derived from angiotensin IV that potently enhances cognitive function by promoting synaptogenesis. It is 10 million times more potent than BDNF at promoting synapse formation through HGF/c-Met receptor activation. ### Mechanism of Action Binds to hepatocyte growth factor (HGF) with high affinity (Kd = 65 pM) and potentiates its activity at c-Met receptor, activating PI3K/AKT pathways and promoting new synaptic connections with extraordinary potency. ### Key Benefits - Dramatic synaptogenesis promotion - 10 million times more potent than BDNF - Cognitive enhancement and memory improvement - Neuroprotection and potential neuroregeneration - Applications for Alzheimer's, TBI, age-related cognitive decline - Oral bioavailability ### Quick Stats Typical Dose 8-10mg oral or 2-5mg injectable (0.5mg/kg based on research) Frequency Once daily in the morning Cycle Duration 4-8 weeks on Storage Oral: room temperature (2 year shelf life); Injectable lyophilized: 2-8°C; Reconstituted: 2-8°C, use within 30 days ## Molecular Information Molecular Weight 504.7 Da Type Modified oligopeptide Half-Life 8-12 days ### Amino Acid Sequence `Hexanoyl-Tyr-Ile-Ahx-NH2` ### Modifications N-terminal hexanoic acid for BBB penetration Enhanced metabolic stability Kd = 65 pM for HGF binding ## Research Indications The following information is derived from published scientific literature and is provided for educational and research reference purposes only. It does not constitute medical advice, diagnosis, or treatment recommendations. These peptides are not approved for human use and are sold exclusively for in-vitro laboratory research. Cognitive Neuroprotection Neuroplasticity ## Dosing Protocols ### oral Oral capsules/tablets are the most convenient form. Take in the morning with or without food. No reconstitution required. | Goal | Dose | Frequency | Route | | --- | --- | --- | --- | | Standard cognitive enhancement | 8-10mg | 1x daily (morning) | Oral | | Low-dose maintenance | 5mg | 1x daily | Oral | | Intensive learning protocol | 10-15mg | 1x daily | Oral | #### Key Tips - No injection required - Room temperature storage (2 year shelf life) - Convenient once-daily dosing ### injectable Subcutaneous/intraperitoneal injection provides more consistent dosing. Requires refrigerated storage after reconstitution. | Goal | Dose | Frequency | Route | | --- | --- | --- | --- | | Research protocol | 0.5mg/kg daily | Daily or 3x weekly | SubQ/IP | | Standard injectable | 2-5mg total | 1x daily | SubQ | #### Key Tips - Abdomen, thigh, or upper arm injection sites - More consistent dosing than oral Reconstitution Instructions ### topical Topical cream formulation with limited research data. Experimental route. | Goal | Dose | Frequency | Route | | --- | --- | --- | --- | | Topical application | 10-20mg cream | 1x daily | Inner forearms, shoulders (rotate sites) | #### Key Tips - Non-invasive - Room temperature storage ## Peptide Interactions #### Semax Compatible Enhanced cognitive benefits; monitor for overstimulation. #### Selank Compatible Synergistic effects; watch for neural overstimulation. #### BPC-157 Compatible Different mechanisms; no negative interactions known. #### P21 Avoid Both affect neuroplasticity strongly; avoid concurrent use. #### Noopept Compatible Some stack for cognition; limited safety data. #### NAD+ Compatible Complementary mechanisms for cellular health. #### Cerebrolysin Monitor Both potently neuroactive; may cause overstimulation. #### TB-500 Compatible Different targets; no known interactions. ## What to Expect Week 1-2 Subtle cognitive shifts; possible headaches during adaptation Week 2-4 Improved focus and memory formation Week 4-8 Peak cognitive benefits and enhanced learning Post-cycle Effects may persist for days to weeks after discontinuation ## Side Effects & Safety #### Common Side Effects - Headaches (most frequent side effect) - Anxiety or overstimulation - Sleep disruption when dosed late in day - Mental clarity increase #### Monitoring - Cognitive function assessment - Mood and anxiety levels - Sleep quality - Requires cycling to prevent tolerance #### Stop Signs - Severe or persistent headaches - Increasing anxiety or panic attacks - Significant mood changes or depression - Sleep disturbance beyond 3 days - Concerning neurological symptoms - Signs of overstimulation or mania - Injection site reactions (if injectable) #### Contraindications - Not FDA approved - research compound only - Theoretical cancer risk via c-Met activation - Cancer history (avoid due to c-Met pathway) - Pregnancy or breastfeeding - No long-term human safety data ## Quality Checklist #### Good Signs - Pharmaceutical-grade from licensed compounding pharmacy - Certificate of analysis showing >98% purity - Proper storage conditions maintained - Uniform capsules with clear lot numbers and expiration dates #### Warning Signs - Research chemical sources may lack pharmaceutical standards - Products lacking third-party testing documentation #### Bad Signs - No analytical testing or purity reports - Unverified sources - Suspicious or extremely cheap pricing - Discolored or damaged capsules ## Research & References ### Latest Research 2024 #### Fosgonimeton (ATH-1017) Phase 2 Trials Clinical Development Phosphate pro-drug of Dihexa currently in Phase 2 clinical trials for Alzheimer's and Parkinson's disease. ### Key References 1. 2013 #### Injectable Route Efficacy Study Intraperitoneal injection at 0.5mg/kg/day completely reversed scopolamine-induced cognitive deficits (p<0.001), with performance indistinguishable from healthy controls. 2. 2021 #### APP/PS1 Alzheimer's Model Study Dihexa restored spatial learning and memory in Morris water maze tests, increased neuronal cells and synaptophysin expression, reduced neuroinflammation. 3. 2014 #### Synaptogenic Potency Study Demonstrated to be 10 million times more effective than BDNF at promoting synapse formation through HGF/c-Met receptor activation. [Search PubMed for Dihexa](https://pubmed.ncbi.nlm.nih.gov/?term=%28%22Dihexa%22%20OR%20%22N-hexanoic-Tyr-Ile-%286%29-aminohexanoic%20amide%22%29) Research Library ## Dihexa research & guides Plain-English guides and study summaries from published literature. [View all 1](https://peptidesupermarket.co.za/research/peptide/dihexa) ![Dihexa Explained: Why This Experimental Compound Is Different From Typical Nootropics](https://peptidesupermarket.co.za/storage/1350/conversions/Dihexa-PepSup-Image-thumbnail.jpg) Guides 7 min ### Dihexa Explained: Why This Experimental Compound Is Different From Typical Nootropics Dihexa is an emerging research compound studied for synaptogenesis and neuroplasticity, rather than short-term stimulation. Its promise is preclinical, with major safety questions still unresolved. Read article [Dihexa Explained: Why This Experimental Compound Is Different From Typical Nootropics](https://peptidesupermarket.co.za/research/dihexa-explained-why-this-experimental-compound-is-different-from-typical-nootropics) --- *Add `.md` to any page URL on peptidesupermarket.co.za for its Markdown version. Index of the site: https://peptidesupermarket.co.za/llms.txt - full text: https://peptidesupermarket.co.za/llms-full.txt.*