--- title: "Cagrilintide Peptide SA - Compare Prices from 9 Suppliers - PeptideSupermarket®" description: "Compare Cagrilintide prices from 9 SA suppliers, from R510.00. Find the cheapest deals, read reviews and save money." url: "https://peptidesupermarket.co.za/peptide/cagrilintide" site: "PeptideSupermarket®" country: "South Africa" --- [Home](https://peptidesupermarket.co.za) › [Peptides](https://peptidesupermarket.co.za/compare-peptide-prices-za) › Cagrilintide Search # Cagrilintide Price Comparison Live prices from 9 SA suppliers, from R510.00, compared side by side so you never overpay. [GLP-1 & metabolic research](https://peptidesupermarket.co.za/compare-peptide-prices-za) Prices checked 33 minutes ago We compare prices & may earn a commission. [Full disclosure](https://peptidesupermarket.co.za/disclosure). Best Price R510.00 Average R1,073.57 Highest R1,900.00 You Could Save 73% 7 results 5mg Compare 7 prices for Cagrilintide. Cheapest: R510.00. Average: R1,073.57. | Compare | Supplier | Price | Price / mg | Stock | Delivery | Quality | Coupon | Visit | | --- | --- | --- | --- | --- | --- | --- | --- | --- | | | [Crono Pharm](https://peptidesupermarket.co.za/suppliers/chrono-pharm) Best Cagrilintide | R510.00 | R102.00/mg | In Stock | R150.00 | Lab Tested | — | Visit | | | [JP Research](https://peptidesupermarket.co.za/suppliers/jp-research) Cagrilintide | R549.00 | R109.80/mg | In Stock | Free | Lab Tested | — | Visit | | | [Striata Labs](https://peptidesupermarket.co.za/suppliers/striata-labs) Cagrilintide 5mg | R600.00 | R120.00/mg | In Stock | R150.00 | Lab Tested | — | Visit | | | [Health & Fitness ZA](https://peptidesupermarket.co.za/suppliers/health-fitness-za) Cagrilintide 5mg | R900.00 | R180.00/mg | Out of Stock | R160.00 | — | — | Visit | | | [Biolabs Peptides](https://peptidesupermarket.co.za/suppliers/biolabs-peptides) Cagrilintide | R1,156.00 | R231.20/mg | In Stock | R185.00 | Lab Tested | — | Visit | | | [SA Peptides](https://peptidesupermarket.co.za/suppliers/sa-peptides) Cagrilintide 5mg | R1,900.00 | R380.00/mg | In Stock | R140.00 | — | — | Visit | | | [Buy Peptides](https://peptidesupermarket.co.za/suppliers/buy-peptides) Cagrilintide 5mg | R1,900.00 | R380.00/mg | In Stock | R250.00 | — | — | Visit | More ways to compare Cagrilintide Different views of the same live SA pricing, tuned for how you like to shop. [Best Cagrilintide Prices Best prices ranked](https://peptidesupermarket.co.za/best-cagrilintide-prices) [Cheapest Cagrilintide Prices Cheapest suppliers compared](https://peptidesupermarket.co.za/cheapest-cagrilintide-prices) [Where to Buy Cagrilintide Full buyer's guide](https://peptidesupermarket.co.za/where-to-buy-cagrilintide) [Buy Cagrilintide Online SA Cheap Today's hottest deals](https://peptidesupermarket.co.za/buy-cagrilintide-online-za-cheap) [Cagrilintide Price Comparison Live price dashboard](https://peptidesupermarket.co.za/cagrilintide-price-comparison) [Cagrilintide SA Supplier Verified SA supplier directory](https://peptidesupermarket.co.za/cagrilintide-za-supplier) [Cagrilintide For Sale Browse listings for sale](https://peptidesupermarket.co.za/cagrilintide-for-sale) Compare another peptide Search PeptideSupermarket® compares prices but doesn't sell products. More All purchases are made directly from third-party suppliers; your relationship is solely with them. We accept no liability for the quality, purity, or legality of any products listed. We may earn a commission when you click through to a supplier and make a purchase. This does not affect pricing information displayed. By using this site you accept responsibility for ensuring purchases comply with applicable laws in your jurisdiction. [Read our full disclosure](https://peptidesupermarket.co.za/disclosure). ## Cagrilintide Profile Extensively Studied Long-Acting Amylin Receptor Agonist | Weight Loss & Diabetes ### Overview Novel long-acting lipidated amylin analog functioning as dual amylin and calcitonin receptor agonist for weight management and type 2 diabetes. Phase 3 trials demonstrate 22.7% weight loss with CagriSema combination. ### Mechanism of Action Subcutaneous injection enables optimal bioavailability, targeting dual amylin and calcitonin receptors for satiety and metabolic regulation. Enhances insulin sensitivity and controls gastric emptying. ### Key Benefits - FDA development candidate with extensive Phase 3 data - Superior weight loss in combination with semaglutide (22.7%) - Once-weekly convenience - 2.2% HbA1c reduction with CagriSema ### Quick Stats Typical Dose 2.4mg weekly (after escalation) Frequency Once weekly, same day each week Cycle Duration Continuous long-term therapy Storage Lyophilized: -20°C frozen; Reconstituted: 2-8°C refrigerated, use within 30 days ## Molecular Information Molecular Weight 4,409.01 Da Length 37 amino acids Type Amylin receptor agonist Half-Life ~7 days (159-195 hours) ### Amino Acid Sequence `37-amino acid peptide` ### Modifications N-terminal lipidation with γ-glutamic acid spacer and C20 fatty diacid Engineered mutations reduce β-sheet formation and fibril propensity ## Research Indications The following information is derived from published scientific literature and is provided for educational and research reference purposes only. It does not constitute medical advice, diagnosis, or treatment recommendations. These peptides are not approved for human use and are sold exclusively for in-vitro laboratory research. Weight Loss Metabolic Appetite Control ## Dosing Protocols ### injectable Subcutaneous injection to abdomen, thigh, or upper arm. Pre-filled pen design when commercially available. | Goal | Dose | Frequency | Route | | --- | --- | --- | --- | | Weight Loss (Monotherapy) | 2.4mg | Once weekly | SubQ | | Weight Loss (CagriSema) | 2.4mg + semaglutide 2.4mg | Once weekly | SubQ | | Type 2 Diabetes Management | 2.4mg weekly | Once weekly | SubQ with metformin | | Dose Escalation Protocol | 0.25mg → 0.5mg → 1.0mg → 1.7mg → 2.4mg | Weekly increases over 16 weeks | SubQ | #### Key Tips - Once-weekly convenience - Pre-filled pen design when approved - Dual receptor targeting Reconstitution Instructions ## Peptide Interactions #### Semaglutide Synergistic CagriSema combination achieves enhanced weight loss through complementary GLP-1 and amylin pathways. #### Tirzepatide Compatible No known direct interactions; different mechanisms allow concurrent use. #### Retatrutide Monitor Compounded GI side effects create substantial risk without specialist supervision. #### Metformin Compatible Well-tolerated in Phase 2/3 trials with no pharmacokinetic interactions. #### SGLT2 Inhibitors Compatible Clinical trials demonstrated safe concurrent use with complementary mechanisms. #### Pramlintide Avoid Both are amylin agonists; combination provides no additional benefit and increases GI risks. #### Oral Contraceptives Monitor Delayed gastric emptying may affect absorption; space administration by 1 hour. ## What to Expect Week 1-2 Gastrointestinal adaptation; mild nausea possible during dose escalation Week 4-8 Early weight loss (2-5%); noticeable appetite reduction Week 12-26 Significant weight loss acceleration (10-15%); improved satiety signals Week 26+ Peak efficacy (15-23% weight loss); sustained maintenance with continued therapy ## Side Effects & Safety #### Common Side Effects - Gastrointestinal effects (nausea, vomiting, diarrhea) during initial weeks - Anti-cagrilintide antibodies develop in 46-73% but do not affect efficacy - Only 57.3% achieved maximum 2.4mg dose in REDEFINE 1 trial #### Monitoring - No clinically significant QT prolongation observed - Monitor for fibril formation in reconstituted solution (must remain clear) #### Stop Signs - Severe persistent nausea/vomiting preventing hydration - Pancreatitis signs (severe abdominal pain radiating to back) - Severe allergic reactions or anaphylaxis - Significant injection site reactions or abscess formation #### Contraindications - Not recommended in pregnancy or breastfeeding - Not yet commercially available (FDA approval expected Q1 2026) ## Quality Checklist #### Good Signs - Pre-filled pen design when approved - Pharmaceutical grade purity >98% - Frozen storage stability at -20°C - Extended stability over 7-day dosing interval #### Warning Signs - Standard bacteriostatic water acceptable short-term but may degrade at neutral pH; optimal stability requires pH ~4.0 #### Bad Signs - Fibril formation at improper pH—solution must remain clear - Aggregation or precipitation indicates degradation ## Research & References ### Key References 1. 2025 #### REDEFINE 1 Trial - Phase 3 Weight Loss 3,417 adults with obesity; 22.7% weight loss with CagriSema vs 2.4% placebo. New England Journal of Medicine. 2. 2025 #### REDEFINE 2 Trial - Phase 3 Type 2 Diabetes 1,206 adults; 15.7% weight loss; 73.5% achieved HbA1c ≤6.5%. New England Journal of Medicine. 3. 2023 #### Phase 2 Type 2 Diabetes Combination Study 32 weeks; 15.6% weight loss; 2.2% HbA1c reduction with CagriSema. The Lancet. [Search PubMed for Cagrilintide](https://pubmed.ncbi.nlm.nih.gov/?term=%28%22Cagrilintide%22%20OR%20%22AM833%22%29) Research Library ## Cagrilintide research & guides Plain-English guides and study summaries from published literature. [View all 1](https://peptidesupermarket.co.za/research/peptide/cagrilintide) ![Cagrilintide Guide: Appetite Control, Satiety and Weight-Loss Research](https://peptidesupermarket.co.za/storage/1496/conversions/Cagrilintide-PEPSUPSA-Image-thumbnail.jpg) Guides 6 min ### Cagrilintide Guide: Appetite Control, Satiety and Weight-Loss Research Cagrilintide is a long-acting amylin analogue being studied for appetite regulation, weight management and type 2 diabetes, including in combination with semaglutide. Read article [Cagrilintide Guide: Appetite Control, Satiety and Weight-Loss Research](https://peptidesupermarket.co.za/research/cagrilintide-guide-appetite-control-satiety-and-weight-loss-research) --- *Add `.md` to any page URL on peptidesupermarket.co.za for its Markdown version. Index of the site: https://peptidesupermarket.co.za/llms.txt - full text: https://peptidesupermarket.co.za/llms-full.txt.*