--- title: "Aicar Peptide SA - Compare Prices from 3 Suppliers - PeptideSupermarket®" description: "Compare Aicar prices from 3 SA suppliers, from R850.00. Find the cheapest deals, read reviews and save money." url: "https://peptidesupermarket.co.za/peptide/aicar" site: "PeptideSupermarket®" country: "South Africa" --- [Home](https://peptidesupermarket.co.za) › [Peptides](https://peptidesupermarket.co.za/compare-peptide-prices-za) › Aicar Search # Aicar Price Comparison Live prices from 3 SA suppliers, from R850.00, compared side by side so you never overpay. [GLP-1 & metabolic research](https://peptidesupermarket.co.za/compare-peptide-prices-za) Prices checked 1 hour ago We compare prices & may earn a commission. [Full disclosure](https://peptidesupermarket.co.za/disclosure). Best Price R850.00 Average R925.00 Highest R1,000.00 You Could Save 15% 2 results 50mg Compare 2 prices for Aicar. Cheapest: R850.00. Average: R925.00. | Compare | Supplier | Price | Price / mg | Stock | Delivery | Quality | Coupon | Visit | | --- | --- | --- | --- | --- | --- | --- | --- | --- | | | [Buy Peptides](https://peptidesupermarket.co.za/suppliers/buy-peptides) Best Aicar 50mg | R850.00 | R17.00/mg | In Stock | R250.00 | — | — | Visit | | | [Buy Peptides](https://peptidesupermarket.co.za/suppliers/buy-peptides) Aicar Nasal | R1,000.00 | R20.00/mg | In Stock | R250.00 | — | — | Visit | More ways to compare Aicar Different views of the same live SA pricing, tuned for how you like to shop. [Best Aicar Prices Best prices ranked](https://peptidesupermarket.co.za/best-aicar-prices) [Cheapest Aicar Prices Cheapest suppliers compared](https://peptidesupermarket.co.za/cheapest-aicar-prices) [Where to Buy Aicar Full buyer's guide](https://peptidesupermarket.co.za/where-to-buy-aicar) [Buy Aicar Online SA Cheap Today's hottest deals](https://peptidesupermarket.co.za/buy-aicar-online-za-cheap) [Aicar Price Comparison Live price dashboard](https://peptidesupermarket.co.za/aicar-price-comparison) [Aicar SA Supplier Verified SA supplier directory](https://peptidesupermarket.co.za/aicar-za-supplier) [Aicar For Sale Browse listings for sale](https://peptidesupermarket.co.za/aicar-for-sale) Compare another peptide Search PeptideSupermarket® compares prices but doesn't sell products. More All purchases are made directly from third-party suppliers; your relationship is solely with them. We accept no liability for the quality, purity, or legality of any products listed. We may earn a commission when you click through to a supplier and make a purchase. This does not affect pricing information displayed. By using this site you accept responsibility for ensuring purchases comply with applicable laws in your jurisdiction. [Read our full disclosure](https://peptidesupermarket.co.za/disclosure). ## Aicar Profile Limited 5-Aminoimidazole-4-carboxamide Ribonucleotide | AMPK Activator ### Overview AICAR is a cell-permeable nucleoside analog that activates AMP-activated protein kinase (AMPK), a key regulator of cellular energy homeostasis. Originally studied for cardiac ischemia protection, it gained attention as an 'exercise mimetic' due to its metabolic effects. ### Mechanism of Action Once inside cells, AICAR is phosphorylated to ZMP, which mimics AMP and activates AMPK. This triggers metabolic pathways typically activated during exercise: increased glucose uptake, fatty acid oxidation, and mitochondrial biogenesis. ### Key Benefits - AMPK pathway activation - Enhanced fatty acid oxidation - Improved glucose uptake - Potential endurance enhancement - Mitochondrial biogenesis stimulation ### Quick Stats Typical Dose 1-5mg daily Frequency Once daily Cycle Duration 8-12 weeks Storage Lyophilized: -20°C; Reconstituted: 2-8°C for 4 weeks ## Molecular Information Molecular Weight 338.21 Da Type Nucleoside analog Half-Life ~2-3 hours ## Research Indications The following information is derived from published scientific literature and is provided for educational and research reference purposes only. It does not constitute medical advice, diagnosis, or treatment recommendations. These peptides are not approved for human use and are sold exclusively for in-vitro laboratory research. Metabolic Performance Cardioprotection ## Dosing Protocols ### injectable Subcutaneous injection once daily. Progressive dosing protocols are common to assess tolerance. | Goal | Dose | Frequency | Route | | --- | --- | --- | --- | | Standard Protocol | 1-3mg | Daily | SubQ | | Gradual Introduction | 1mg → 2mg → 3mg | Daily, titrating over 4 weeks | SubQ | | Advanced Protocol | 3-5mg | Daily for 8-12 weeks | SubQ | #### Key Tips - Direct AMPK activation - Once daily dosing - Stable when reconstituted properly Reconstitution Instructions ## Peptide Interactions #### Metformin Monitor Both activate AMPK through different mechanisms. Combined use may have additive effects on glucose metabolism. #### GW501516 Synergistic Different pathways (AMPK vs PPARδ) that may complement metabolic effects. Popular research combination. #### SR9009 Synergistic Rev-ErbA agonist with complementary metabolic effects. ## What to Expect Week 1-2 Subtle changes in energy levels; body adjusting to AMPK activation Week 3-4 Potential improvements in endurance capacity and metabolic markers Week 5-8 Cumulative metabolic adaptations; enhanced fat oxidation Week 8-12 Full effects on mitochondrial density and metabolic efficiency ## Side Effects & Safety #### Common Side Effects - Injection site reactions - Mild fatigue during adaptation - Potential hypoglycemia #### Monitoring - Not FDA-approved for any indication - WADA prohibited substance - Monitor blood glucose, especially if diabetic - Limited human safety data at research doses #### Stop Signs - Severe hypoglycemia symptoms - Lactic acidosis symptoms (muscle pain, weakness, difficulty breathing) - Unusual cardiac symptoms - Severe fatigue or weakness #### Contraindications - Diabetes (risk of hypoglycemia) - Cardiac conditions - Pregnancy or breastfeeding - Competitive athletes (WADA prohibited) ## Quality Checklist #### Good Signs - White to off-white lyophilized powder - Clear solution after reconstitution - Certificate of Analysis with purity testing #### Warning Signs - Slight yellowing may occur but should dissolve clearly #### Bad Signs - Discolored or clumped powder - Cloudy solution after reconstitution - Particulate matter visible ## Research & References ### Key References 1. 2012 #### AMPK and Exercise: Glucose Uptake and Insulin Sensitivity Review of AMPK role in exercise-induced metabolic adaptations and AICAR as pharmacological activator. 2. 2008 #### AICAR Mouse Endurance Study Mice treated with AICAR showed 44% increase in running endurance without training. [Search PubMed for Aicar](https://pubmed.ncbi.nlm.nih.gov/?term=%28%22Aicar%22%20OR%20%225-Aminoimidazole-4-carboxamide%20ribonucleotide%22%20OR%20%22Acadesine%22%20OR%20%22AICA-Riboside%22%20OR%20%22ZMP%20precursor%22%29) --- *Add `.md` to any page URL on peptidesupermarket.co.za for its Markdown version. Index of the site: https://peptidesupermarket.co.za/llms.txt - full text: https://peptidesupermarket.co.za/llms-full.txt.*